Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | MAOB | P27338 | 4/20 | 0.81 |
| ▸ | BCHE | P06276 | 3/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.81 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.81 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.81 |
| ▸ | ACHE | P22303 | 1/20 | 0.81 |
| ▸ | RECQL | P46063 | 1/20 | 0.81 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.81 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.76 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.76 |
| ▸ | RELA | Q04206 | 2/20 | 0.76 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.76 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.76 |
| ▸ | PKM | P14618 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25202483 | 1.00 | CYP1B1 (0.81) | CYP1B1MAPTMAOBBCHELMNA | |
| SCHEMBL25193884 | 1.00 | CYP1B1 (0.81) | CYP1B1MAPTMAOBBCHELMNA | |
| SCHEMBL25214545 | 1.00 | CYP1B1 (0.81) | CYP1B1MAPTMAOBBCHELMNA | |
| Chalcone SCHEMBL4385450 | 0.96 | CYP1B1 (0.88) | CYP1B1MAPTMAOBBCHELMNA | |
| Chalcone SCHEMBL4385453 | 0.96 | CYP1B1 (0.88) | CYP1B1MAPTMAOBBCHELMNA | |
| SCHEMBL27541712 | 0.94 | CYP1B1 (0.78) | CYP1B1MAPTMAOBBCHELMNA | |
| SCHEMBL5196588 | 0.94 | CYP1B1 (0.78) | CYP1B1MAPTMAOBBCHELMNA | |
| SCHEMBL5196586 | 0.94 | CYP1B1 (0.78) | CYP1B1MAPTMAOBBCHELMNA | |
| SCHEMBL9915665 | 0.94 | CYP1B1 (0.91) | CYP1B1MAPTMAOBBCHELMNA | |
| SCHEMBL8431772 | 0.94 | CYP1B1 (0.91) | CYP1B1MAPTMAOBBCHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8242175-B2 | Class of histone deacetylase inhibitors | DAC S.R.L. (IT) | 2012-08-14 | — | — | US | disclosed |
| US-20110077247-A1 | CLASS OF HISTONE DEACETYLASE INHIBITORS | DAC S.r.I. (IT) | 2011-03-31 | — | — | US | disclosed |
| US-20100113438-A1 | CLASS OF HISTONE DEACETYLASE INHIBITORS | DAC S.R.L. (IT) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077247-A1 | CLASS OF HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC11 | CYP1B1 2427/4885MAPT 4648/4885MAOB 1703/4885 |
| US-20100113438-A1 | CLASS OF HISTONE DEACETYLASE INHIBITORS | HDAC3, HDAC1, HDAC11 | CYP1B1 2427/4885MAPT 4648/4885MAOB 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.