Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385649 | 1.00 | ADRB2 (0.70) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL4392993 | 1.00 | ADRB2 (0.70) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL13589418 | 0.90 | ADRB2 (0.73) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL27654126 | 0.90 | ADRB2 (0.77) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL4386830 | 0.90 | ADRB2 (0.77) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL4386838 | 0.90 | ADRB2 (0.77) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL10655941 | 0.90 | ADRB2 (0.78) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL12333351 | 0.87 | ADRB2 (0.52) | ADRB2ADRB1 | |
| SCHEMBL4385163 | 0.86 | ADRB2 (0.76) | ADRB2ADRB1CYP1A2CYP2D6TSHR | |
| SCHEMBL4385168 | 0.86 | ADRB2 (0.76) | ADRB2ADRB1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629358-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629358-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629358-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| US-20050234097-A1 | Compounds useful for the treatment of diseases | PFIZER INC | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234097-A1 | Compounds useful for the treatment of diseases | LTC4S, CYP11B2, CYP11B1 | ADRB2 731/4885ADRB1 711/4885CYP1A2 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.