Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 9/20 | 0.36 |
| ▸ | GABRD | O14764 | 9/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 9/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 9/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 9/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 9/20 | 0.36 |
| ▸ | GABRE | P78334 | 9/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 9/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 9/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 9/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28139742 | 0.82 | GRIN1 (0.41) | GRIN1GRIN2BGABRPGABRDGABRA1 | |
| SCHEMBL1173075 | 0.82 | GRIN1 (0.41) | GRIN1GRIN2BGABRPGABRDGABRA1 | |
| SCHEMBL19655773 | 0.82 | GRIN1 (0.42) | GRIN1GRIN2BGABRPGABRDGABRA1 | |
| SCHEMBL20326258 | 0.82 | GRIN1 (0.42) | GRIN1GRIN2BGABRPGABRDGABRA1 | |
| SCHEMBL22072807 | 0.80 | GRIN1 (0.42) | GRIN1GRIN2BGABRPGABRDGABRA1 | |
| SCHEMBL22072638 | 0.79 | GABRP (0.46) | GRIN1GRIN2BGABRPGABRDGABRA1 | |
| SCHEMBL5320301 | 0.78 | GRIN1 (0.40) | GRIN1GRIN2BGABRPGABRDGABRA1 | |
| SCHEMBL19242333 | 0.78 | GABRA1 (0.45) | GRIN1GRIN2BGABRPGABRDGABRA1 | |
| SCHEMBL19242421 | 0.78 | GABRA1 (0.45) | GRIN1GRIN2BGABRPGABRDGABRA1 | |
| SCHEMBL11578602 | 0.77 | GRIN1 (0.39) | GRIN1GRIN2BGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1906969-A4 | METHODS FOR TREATING AND DIAGNOSING COMPLICATIONS OF PREMATURE BIRTH | CHILDRENS MEDICAL CENTER (US) | 2009-07-29 | — | — | EP | disclosed |
| EP-1906969-A2 | METHODS FOR TREATING AND DIAGNOSING COMPLICATIONS OF PREMATURE BIRTH | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007011926-A2 | METHODS FOR TREATING AND DIAGNOSING COMPLICATIONS OF PREMATURE BIRTH | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2007-01-25 | — | — | WO | disclosed |