Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384582 | 0.91 | GPR119 (0.42) | KDM4EPKMFPR2MEN1ALDH1A1 | |
| SCHEMBL4383288 | 0.88 | HRH3 (0.56) | FPR2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4395383 | 0.86 | GPR119 (0.44) | FPR2GPR119 | |
| SCHEMBL123942 | 0.78 | MEN1 (0.52) | KDM4EPKMMEN1ALDH1A1MAPT | |
| SCHEMBL1774237 | 0.77 | MEN1 (0.51) | KDM4EPKMMEN1ALDH1A1MAPT | |
| SCHEMBL25832564 | 0.77 | FPR2 (0.48) | KDM4EPKMFPR2MAPTGPR119 | |
| SCHEMBL5573169 | 0.75 | HPGD (0.53) | KDM4EPKMALDH1A1MAPTGPR119 | |
| SCHEMBL15770892 | 0.75 | FPR2 (0.47) | KDM4EPKMFPR2MAPTGPR119 | |
| SCHEMBL1772547 | 0.75 | GPR119 (0.51) | KDM4EPKMMEN1ALDH1A1MAPT | |
| SCHEMBL189570 | 0.74 | FPR2 (0.51) | KDM4EPKMFPR2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181948-A1 | DIAMINE DERIVATIVE | ARG1, PRMT5, PRMT1 | KDM4E 418/4885PKM 3834/4885FPR2 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.