Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.32 |
| ▸ | THRB | P10828 | 4/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383591 | 0.83 | ADRA2A (0.37) | THRBLMNAGAAKMT2A | |
| SCHEMBL10000937 | 0.69 | THRB (0.40) | THRATHRBLMNA | |
| SCHEMBL2104464 | 0.68 | CYP19A1 (0.36) | KDM4E | |
| SCHEMBL4386723 | 0.68 | KDM4E (0.32) | KDM4ELMNAGAAKMT2A | |
| SCHEMBL2104158 | 0.67 | CHRM2 (0.41) | KDM4ELMNA | |
| SCHEMBL16804564 | 0.67 | THRB (0.39) | THRATHRBLTA4HLMNAGAA | |
| SCHEMBL10550592 | 0.67 | ADRA2A (0.39) | — | |
| SCHEMBL2103259 | 0.66 | CES2 (0.31) | — | |
| SCHEMBL2104730 | 0.66 | TSHR (0.43) | GAAKMT2A | |
| SCHEMBL18933828 | 0.64 | THRB (0.36) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | disclosed |