Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27515725 | 0.99 | L3MBTL1 (0.78) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| SCHEMBL6994948 | 0.87 | L3MBTL1 (0.97) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| SCHEMBL994183 | 0.85 | L3MBTL1 (0.58) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| Tert-Butylamine SCHEMBL28089931 | 0.83 | L3MBTL1 (0.83) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| SCHEMBL28663269 | 0.82 | L3MBTL1 (0.62) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| SCHEMBL21061969 | 0.82 | L3MBTL1 (0.82) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| SCHEMBL21061629 | 0.82 | L3MBTL1 (0.82) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| Hydrochloric Acid SCHEMBL27563112 | 0.81 | L3MBTL1 (0.64) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| SCHEMBL5841484 | 0.81 | L3MBTL1 (0.54) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 | |
| SCHEMBL2495181 | 0.80 | L3MBTL1 (0.62) | L3MBTL1KDM4ECYP2C19POLBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298820-A1 | 3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | WYETH (US) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298820-A1 | 3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES | MTOR, PIK3CA, PIK3C2B | L3MBTL1 4738/4885KDM4E 738/4885CYP2C19 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.