Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butylamine SCHEMBL28089931 | 0.92 | L3MBTL1 (0.83) | L3MBTL1KDM4ESMN1; SMN2CYP2C19POLB | |
| SCHEMBL21061969 | 0.92 | L3MBTL1 (0.82) | L3MBTL1KDM4ESMN1; SMN2CYP2C19POLB | |
| SCHEMBL21061629 | 0.92 | L3MBTL1 (0.82) | L3MBTL1KDM4ESMN1; SMN2CYP2C19POLB | |
| SCHEMBL4387098 | 0.87 | L3MBTL1 (0.75) | L3MBTL1KDM4ESMN1; SMN2CYP2C19POLB | |
| Hydrochloric Acid SCHEMBL27515725 | 0.86 | L3MBTL1 (0.78) | L3MBTL1KDM4ESMN1; SMN2CYP2C19POLB | |
| SCHEMBL13905827 | 0.85 | L3MBTL1 (0.72) | L3MBTL1KDM4ESMN1; SMN2CYP2C19POLB | |
| SCHEMBL30370085 | 0.85 | L3MBTL1 (0.72) | L3MBTL1KDM4ESMN1; SMN2CYP2C19POLB | |
| SCHEMBL27714486 | 0.82 | SIGMAR1 (0.70) | L3MBTL1KDM4ESMN1; SMN2CYP2C19POLB | |
| SCHEMBL6995476 | 0.81 | L3MBTL1 (0.67) | L3MBTL1KDM4ESMN1; SMN2CYP2C19POLB | |
| SCHEMBL21207066 | 0.79 | L3MBTL1 (0.64) | L3MBTL1KDM4ESMN1; SMN2CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145483-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER AND METHODS OF MAKING AND USING THE SAME | HTG MOLECULAR DIAGNOSTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| EP-0874809-B1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2003-08-27 | — | — | EP | disclosed |
| US-6239175-B1 | Carbamoyloxy derivatives of mutiline and their use as antibacterials | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-29 | — | — | US | disclosed |
| US-6020368-A | MICROBIOCIDES | HINKS JEREMY DAVID (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0874809-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997025309-A1 | CARBAMOYLOXY DERIVATIVES OF MUTILINE AND THEIR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 1997-07-17 | — | — | WO | disclosed |