Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653473 | 0.78 | CHRM2 (0.49) | CHRM2MAPT | |
| Hydrochloric Acid SCHEMBL2158162 | 0.77 | CHRM2 (0.48) | CHRM2MAPT | |
| SCHEMBL4387371 | 0.76 | HPGD (0.32) | ALDH1A1GAAMAPT | |
| SCHEMBL14829368 | 0.75 | TAAR1 (0.53) | TAAR1 | |
| SCHEMBL28036038 | 0.75 | PNMT (0.45) | TAAR1ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL3653474 | 0.72 | ATM (0.36) | ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL31143634 | 0.71 | ALDH1A1 (0.34) | TAAR1ALDH1A1KDM4E | |
| SCHEMBL240617 | 0.71 | ALDH1A1 (0.34) | TAAR1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL2158165 | 0.71 | ALDH1A1 (0.36) | ALDH1A1GAAMAPTKDM4E | |
| SCHEMBL20584031 | 0.70 | HSPA5 (0.36) | TAAR1CHRM2ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121054-A2 | SURFACE BOUND ACTIVES | Smith & Nephew, PLC (GB) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008099152-A2 | SURFACE BOUND ACTIVES | SMITH & NEPHEW PLC (GB) | 2008-08-21 | — | — | WO | disclosed |