Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442077 | 0.85 | NR4A2 (0.45) | EGFRNR4A2L3MBTL1ACHEGRIN1 | |
| SCHEMBL442131 | 0.85 | NR4A2 (0.45) | EGFRNR4A2L3MBTL1NCF1RAB9A | |
| SCHEMBL439824 | 0.76 | NR4A2 (0.65) | NR4A2L3MBTL1NCF1RAB9AKDM4E | |
| SCHEMBL438193 | 0.73 | NR4A2 (0.51) | NR4A2L3MBTL1NCF1KDM4ETDP1 | |
| SCHEMBL440270 | 0.70 | NR4A2 (0.62) | NR4A2L3MBTL1NCF1NPSR1KDM4E | |
| SCHEMBL437502 | 0.70 | NCF1 (0.59) | NR4A2NCF1KDM4ETDP1HTT | |
| SCHEMBL436731 | 0.69 | KDM4E (0.56) | NR4A2NCF1RAB9AKDM4ETDP1 | |
| SCHEMBL5264894 | 0.68 | PRNP (0.62) | EGFRACHEGRIN1GRIN2ABCHE | |
| SCHEMBL436969 | 0.68 | NR4A2 (0.46) | NR4A2NCF1RAB9AKDM4ETDP1 | |
| SCHEMBL7186476 | 0.67 | NPSR1 (0.52) | EGFRL3MBTL1RAB9APRNPNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |