Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438758 | 0.85 | EGFR (0.49) | NR4A2NCF1NOS3NOS1NOS2 | |
| SCHEMBL17506377 | 0.81 | HTT (0.42) | NOS3NOS1NOS2KDM4ETDP1 | |
| SCHEMBL436731 | 0.81 | KDM4E (0.56) | NR4A2NCF1NOS3NOS1NOS2 | |
| SCHEMBL440270 | 0.78 | NR4A2 (0.62) | NR4A2NCF1NOS3NOS1NOS2 | |
| SCHEMBL437498 | 0.77 | NOS2 (0.50) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL439824 | 0.76 | NR4A2 (0.65) | NR4A2NCF1KDM4ETDP1HTT | |
| SCHEMBL439581 | 0.76 | ACHE (0.51) | NCF1KDM4ETDP1KMT2AALDH1A1 | |
| SCHEMBL442077 | 0.74 | NR4A2 (0.45) | NR4A2NCF1KDM4ETDP1KMT2A | |
| SCHEMBL438193 | 0.73 | NR4A2 (0.51) | NR4A2NCF1KDM4ETDP1KMT2A | |
| SCHEMBL439148 | 0.73 | NR4A2 (0.40) | NR4A2NCF1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |