Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21291535 | 0.76 | CHEK1 (0.39) | MAPK1ALDH1A1LMNATHRBTSHR | |
| SCHEMBL21582003 | 0.72 | SMN1; SMN2 (0.38) | MAPK1ALDH1A1LMNATHRBTSHR | |
| SCHEMBL28110966 | 0.61 | LMNA (0.35) | MAPK1ALDH1A1LMNATHRBTSHR | |
| SCHEMBL220662 | 0.58 | CYP19A1 (0.50) | MAPK1ALDH1A1LMNATSHRMAPT | |
| SCHEMBL3635116 | 0.57 | HTT (0.33) | ALDH1A1 | |
| SCHEMBL28693465 | 0.57 | HTT (0.33) | ALDH1A1 | |
| SCHEMBL18418866 | 0.57 | CHEK1 (0.40) | MAPK1ALDH1A1LMNATHRBTSHR | |
| SCHEMBL17453581 | 0.55 | MAPT (0.41) | ALDH1A1LMNAMAPTPOLB | |
| SCHEMBL19327235 | 0.55 | ERN1 (0.57) | MAPK1ALDH1A1TSHRMAPT | |
| SCHEMBL2085076 | 0.54 | ALDH1A1 (0.63) | MAPK1ALDH1A1LMNATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363705-A4 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2009-08-12 | — | — | EP | disclosed |
| EP-1363705-A1 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002062423-A1 | COMPOSITION AND ANTIVIRAL ACTIVITY OF SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-15 | — | — | WO | disclosed |