Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | DRD3 | P35462 | 6/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.42 |
| ▸ | HRH1 | P35367 | 5/20 | 0.42 |
| ▸ | DRD4 | P21917 | 5/20 | 0.42 |
| ▸ | DRD5 | P21918 | 5/20 | 0.42 |
| ▸ | HRH2 | P25021 | 5/20 | 0.42 |
| ▸ | HTR7 | P34969 | 5/20 | 0.42 |
| ▸ | HTR6 | P50406 | 5/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | DRD1 | P21728 | 3/20 | 0.42 |
| ▸ | HTR5A | P47898 | 3/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4395310 | 0.96 | TACR1 (0.46) | TACR1KCNH2HTR2ADRD3OPRK1 | |
| SCHEMBL8217473 | 0.88 | DRD4 (0.45) | TACR1KCNH2HTR2ADRD3OPRK1 | |
| SCHEMBL8225045 | 0.87 | SLC6A3 (0.51) | KCNH2HTR2ADRD3OPRK1SLC6A3 | |
| Oxalic Acid SCHEMBL4380272 | 0.84 | HTR2A (0.48) | TACR1KCNH2HTR2ADRD3OPRK1 | |
| SCHEMBL4385355 | 0.83 | CACNA1B (0.46) | TACR1KCNH2HTR2ADRD3OPRK1 | |
| Oxalic Acid SCHEMBL4380546 | 0.82 | SLC6A3 (0.54) | TACR1KCNH2HTR2ADRD3OPRK1 | |
| SCHEMBL4390287 | 0.81 | SIGMAR1 (0.51) | KCNH2HTR2ADRD3OPRK1SLC6A3 | |
| SCHEMBL13588930 | 0.80 | DRD3 (0.46) | KCNH2HTR2ADRD3OPRK1SLC6A3 | |
| SCHEMBL8219712 | 0.80 | HTR2A (0.44) | KCNH2HTR2ADRD3OPRK1SLC6A3 | |
| SCHEMBL13588937 | 0.79 | SLC6A3 (0.54) | KCNH2HTR2ADRD3OPRK1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298878-A1 | OXIME COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA L.P. | 2009-12-03 | — | — | US | disclosed |
| US-20090298878-A1 | OXIME COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA L.P. | 2009-12-03 | — | — | US | disclosed |
| US-20090298878-A1 | OXIME COMPOUNDS AND THE USE THEREOF | PURDUE PHARMA L.P. | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298878-A1 | OXIME COMPOUNDS AND THE USE THEREOF | KCNN4, CACNA1A, KCNN3 | TACR1 381/4885KCNH2 50/4885HTR2A 956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.