Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12827371 | 0.88 | CYP2C9 (0.46) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL31483078 | 0.85 | CYP2C9 (0.54) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL12332384 | 0.83 | NPSR1 (0.49) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL12662749 | 0.81 | CPB2 (0.50) | MTNR1AKDM4EF13A1QPCTQPCTL | |
| SCHEMBL12662747 | 0.81 | CPB2 (0.48) | NAMPTMTNR1AKDM4EF13A1QPCT | |
| SCHEMBL13256665 | 0.80 | CPB2 (0.41) | TSHRCYP2C19NAMPTMTNR1AKDM4E | |
| SCHEMBL12662753 | 0.80 | PIK3CG (0.40) | MTNR1AKDM4EF13A1QPCTQPCTL | |
| SCHEMBL12827372 | 0.79 | CYP2C9 (0.44) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL2084230 | 0.79 | ALDH1A1 (0.48) | CYP2C9TSHRCYP2C19MTORHRH4 | |
| SCHEMBL18381371 | 0.79 | NAMPT (0.43) | CYP2C9TSHRCYP2C19MTORHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219970-A1 | DIHYDROCHROMENE DERIVATIVES | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-13 | — | — | US | disclosed |
| US-11639357-B2 | Dihydrochromene derivatives | Sumitomo Pharma Co., Ltd. (JP) | 2023-05-02 | — | — | US | disclosed |
| US-20210002290-A1 | DIHYDROCHROMENE DERIVATIVES | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-01-07 | — | — | US | disclosed |
| US-10807993-B2 | Dihydrochromene derivatives | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-10-20 | — | — | US | disclosed |
| US-20200216461-A1 | DIHYDROCHROMENE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-07-09 | — | — | US | disclosed |
| US-8524694-B2 | Aminoalkylsterol compounds with antitumoral and neuroprotective activity | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2013-09-03 | — | — | US | disclosed |
| US-20110275604-A1 | AMINOALKYLSTEROL COMPOUNDS WITH ANTITUMORAL AND NEUROPROTECTIVE ACTIVITY | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-11-10 | — | — | US | disclosed |
| US-7947668-B2 | Aminoalkyl sterol compounds having an anti-tumoral and neuroprotective activity | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 2011-05-24 | — | — | US | disclosed |
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |
| EP-1051176-A4 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARM PROD INC (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1051176-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | Aventis Pharmaceuticals Products Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037304-A1 | SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS | AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) | 1999-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275604-A1 | AMINOALKYLSTEROL COMPOUNDS WITH ANTITUMORAL AND NEUROPROTECTIVE ACTIVITY | CYP27A1, NLN, NR1H3 | CYP2C9 3756/4885TSHR 4063/4885CYP2C19 2860/4885 |
| US-20200216461-A1 | DIHYDROCHROMENE DERIVATIVE | H1-3, H1-2, TPD52L2 | CYP2C9 3402/4885TSHR 1895/4885CYP2C19 2567/4885 |
| US-20210002290-A1 | DIHYDROCHROMENE DERIVATIVES | H1-3, H1-2, H1-0 | CYP2C9 3352/4885TSHR 1891/4885CYP2C19 2507/4885 |
| US-11639357-B2 | Dihydrochromene derivatives | H1-3, H1-2, H1-0 | CYP2C9 3352/4885TSHR 1891/4885CYP2C19 2507/4885 |
| US-20230219970-A1 | DIHYDROCHROMENE DERIVATIVES | H1-3, H1-2, H1-0 | CYP2C9 3352/4885TSHR 1891/4885CYP2C19 2507/4885 |
| US-10807993-B2 | Dihydrochromene derivatives | H1-3, H1-2, H1-0 | CYP2C9 3352/4885TSHR 1891/4885CYP2C19 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.