SCHEMBL4388734

SCHEMBL4388734

CCCCCCCCOC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 4/20 0.40
EPHX2 P34913 2/20 0.36
ALDH1A1 P00352 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
LPAR3 Q9UBY5 6/20 0.33
LPAR2 Q9HBW0 5/20 0.33
LPAR1 Q92633 2/20 0.33
RECQL P46063 2/20 0.32
GLA P06280 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
BLM P54132 1/20 0.32
TERT O14746 1/20 0.32
UCHL3 P15374 1/20 0.32
AKT1 P31749 1/20 0.32
MAPK14 Q16539 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4558155 1.00 GBA1 (0.40) GBA1EPHX2ALDH1A1TDP1LPAR3
SCHEMBL7843304 1.00 GBA1 (0.40) GBA1EPHX2ALDH1A1TDP1LPAR3
SCHEMBL8416438 1.00 GBA1 (0.40) GBA1EPHX2ALDH1A1TDP1LPAR3
SCHEMBL39230 1.00 GBA1 (0.40) GBA1EPHX2ALDH1A1TDP1LPAR3
Bromide SCHEMBL11178166 0.98 GBA1 (0.39) GBA1EPHX2ALDH1A1TDP1LPAR3
SCHEMBL8523388 0.98 GBA1 (0.37) GBA1EPHX2ALDH1A1TDP1LPAR3
Ether SCHEMBL8473922 0.93 GBA1 (0.36) GBA1EPHX2ALDH1A1TDP1LPAR3
SCHEMBL12214257 0.92 GAA (0.33) GBA1EPHX2RECQLGAA
SCHEMBL19845811 0.92 GAA (0.35) GAA
SCHEMBL19834225 0.92 GAA (0.35) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8668850-B2 Flame-retarded foamed plastic compositions and shaped articles DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2014-03-11 US disclosed
EP-1889869-B1 Flame-retarded foamed plastic compositions and shaped articles DAI ICHI KOGYO SEIYAKU CO LTD (JP) 2009-11-25 EP disclosed
EP-1889869-A1 Flame-retarded foamed plastic compositions and shaped articles Dai-Ichi Kogyo Seiyaku Co., Ltd. (JP) 2008-02-20 EP disclosed
EP-1712586-B1 Flame-retarded foamed plastic compositions and shaped articles DAI ICHI F R CO LTD (JP) 2007-11-07 EP disclosed
EP-1712586-A1 Flame-retarded foamed plastic compositions and shaped articles Dai-Ichi F R Co., Ltd. (JP) 2006-10-18 EP disclosed
US-20060229372-A1 Flame-retarded foamed plastic compositions and shaped articles DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2006-10-12 US disclosed
EP-0634450-B1 Polyether with releasably bound sterically hindered amines as stabilizing agents CIBA GEIGY AG (CH) 1999-09-08 EP disclosed
US-5534618-A Polyethers containing hindered amines which can be cleaved off as stabilizers CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed
EP-0634450-A2 Polyether with releasably bound sterically hindered amines as stabilizing agents CIBA-GEIGY AG (CH) 1995-01-18 EP disclosed