SCHEMBL8523388

SCHEMBL8523388

CCCCCOC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 3/20 0.37
EPHX2 P34913 1/20 0.37
GAA P10253 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LPAR3 Q9UBY5 6/20 0.31
LPAR2 Q9HBW0 5/20 0.31
LPAR1 Q92633 2/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4558155 0.98 GBA1 (0.40) GBA1EPHX2GAAALDH1A1TDP1
SCHEMBL7843304 0.98 GBA1 (0.40) GBA1EPHX2GAAALDH1A1TDP1
SCHEMBL4388734 0.98 GBA1 (0.40) GBA1EPHX2GAAALDH1A1TDP1
SCHEMBL8416438 0.98 GBA1 (0.40) GBA1EPHX2GAAALDH1A1TDP1
SCHEMBL39230 0.98 GBA1 (0.40) GBA1EPHX2GAAALDH1A1TDP1
Bromide SCHEMBL11178166 0.96 GBA1 (0.39) GBA1EPHX2GAAALDH1A1TDP1
SCHEMBL12214257 0.94 GAA (0.33) GBA1EPHX2GAA
Ether SCHEMBL8473922 0.92 GBA1 (0.36) GBA1EPHX2ALDH1A1TDP1LPAR3
SCHEMBL19834225 0.90 GAA (0.35) GAA
SCHEMBL19845811 0.90 GAA (0.35) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8192904-B2 Electrophotographic photoconductor, and image forming apparatus and process cartridge using the same RICOH COMPANY, LTD. (JP) 2012-06-05 US disclosed
US-20070292780-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) 2007-12-20 US disclosed
EP-0634449-B1 Polyether with sterically hindered amine side chains as stabilizing agents CIBA GEIGY AG (CH) 1999-09-01 EP disclosed
US-5719257-A OBTAINED BY ANIONIC POLYMERIZATION OF DERIVATIVES OF 2,2,6,6-TETRAMETHYL-4-/2,3-EPOXYPROPOXY/PIPERIDINE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-02-17 US disclosed
US-5616637-A PHOTOSTABILITY; OXIDTION AND HEAT RESISTANT CIBA-GEIGY CORPORATION (US) 1997-04-01 US disclosed
US-5521282-A FROM 4-/2,3-EPOXYPROPOXY/-2,2,6,6-TETRAMETHYLPIPERIDINE CIBA-GEIGY CORPORATION (US) 1996-05-28 US disclosed
EP-0634449-A2 Polyether with sterically hindered amine side chains as stabilizing agents CIBA-GEIGY AG (CH) 1995-01-18 EP disclosed