SCHEMBL4558155

SCHEMBL4558155

CCCCCCCCCCCCCCCCOC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 4/20 0.40
EPHX2 P34913 2/20 0.36
ALDH1A1 P00352 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
LPAR3 Q9UBY5 6/20 0.33
LPAR2 Q9HBW0 5/20 0.33
LPAR1 Q92633 2/20 0.33
RECQL P46063 2/20 0.32
GLA P06280 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
BLM P54132 1/20 0.32
TERT O14746 1/20 0.32
UCHL3 P15374 1/20 0.32
AKT1 P31749 1/20 0.32
MAPK14 Q16539 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4388734 1.00 GBA1 (0.40) GBA1EPHX2ALDH1A1TDP1LPAR3
SCHEMBL7843304 1.00 GBA1 (0.40) GBA1EPHX2ALDH1A1TDP1LPAR3
SCHEMBL8416438 1.00 GBA1 (0.40) GBA1EPHX2ALDH1A1TDP1LPAR3
SCHEMBL39230 1.00 GBA1 (0.40) GBA1EPHX2ALDH1A1TDP1LPAR3
Bromide SCHEMBL11178166 0.98 GBA1 (0.39) GBA1EPHX2ALDH1A1TDP1LPAR3
SCHEMBL8523388 0.98 GBA1 (0.37) GBA1EPHX2ALDH1A1TDP1LPAR3
Ether SCHEMBL8473922 0.93 GBA1 (0.36) GBA1EPHX2ALDH1A1TDP1LPAR3
SCHEMBL12214257 0.92 GAA (0.33) GBA1EPHX2RECQLGAA
SCHEMBL19845811 0.92 GAA (0.35) GAA
SCHEMBL19834225 0.92 GAA (0.35) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7105590-B2 Phenolfree stabilization of polyolefins CLARIANT FINANCE (BVI) LIMITED (VG) 2006-09-12 US claimed
CN-115175958-A Polyolefin compositions 巴斯夫欧洲公司 2022-10-11 CN disclosed
CN-113166467-A Polyethylene or polypropylene articles 巴斯夫欧洲公司 2021-07-23 CN disclosed
CN-113166468-A Polypropylene composition 巴斯夫欧洲公司 2021-07-23 CN disclosed
CN-108495888-B Additive mixture for stabilizing polyols and polyurethanes 巴斯夫欧洲公司 2021-03-02 CN disclosed
CN-110809600-A Polyethylene pipe 巴斯夫欧洲公司 2020-02-18 CN disclosed
CN-105636954-B Triazine, piperidine and pyrrolidinyl hindered amine light stabilizers 巴斯夫欧洲公司 2019-12-13 CN disclosed
US-9550886-B2 Stabilizer and composition including the same DOUBLE BOND CHEMICAL IND., CO., LTD. (TW) 2017-01-24 US disclosed
US-20160090468-A1 FLAME RETARDANT, FLAME RETARDANT COMPOSITION, AND MOLDED PRODUCT AND MANUFACTURING METHOD THEREOF DOUBLE BOND CHEMICAL IND., CO., LTD. (TW) 2016-03-31 US disclosed
US-9139713-B2 Stabilizer and composition including the same DOUBLE BOND CHEMICAL IND., CO., LTD. (TW) 2015-09-22 US disclosed
US-20150141557-A1 STABILIZER AND COMPOSITION INCLUDING THE SAME DOUBLE BOND CHEMICAL IND., CO., LTD. (TW) 2015-05-21 US disclosed
US-20150038622-A1 STABILIZER AND COMPOSITION INCLUDING THE SAME DOUBLE BOND CHEMICAL IND., CO., LTD. (TW) 2015-02-05 US disclosed
US-8519049-B2 Curable composition CEMEDINE CO., LTD. (JP) 2013-08-27 US disclosed
US-20120316253-A1 CURABLE COMPOSITION SAITO ATSUSHI (JP) 2012-12-13 US disclosed
US-20090118401-A1 Curable Composition CEMEDINE CO., LTD. (JP) 2009-05-07 US disclosed
US-7105590-B2 Phenolfree stabilization of polyolefins CLARIANT FINANCE (BVI) LIMITED (VG) 2006-09-12 US disclosed
EP-1417257-B1 PHENOLFREE STABILIZATION OF POLYOLEFINS CLARIANT FINANCE BVI LTD (VG) 2005-02-09 EP disclosed
US-20040186207-A1 Phenolfree stabilization of polyolefins CLARIANT FINANCE (BVI) LIMITED (VG) 2004-09-23 US disclosed
EP-1417257-A1 PHENOLFREE STABILIZATION OF POLYOLEFINS Clariant Finance (BVI) Limited (VG) 2004-05-12 EP disclosed
WO-2003014213-A1 PHENOLFREE STABILIZATION OF POLYOLEFINS CLARIANT INTERNATIONAL LTD (CH) 2003-02-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141557-A1 STABILIZER AND COMPOSITION INCLUDING THE SAME APOB, ALB, SMN1; SMN2 GBA1 703/4885EPHX2 2017/4885ALDH1A1 1306/4885
US-20160090468-A1 FLAME RETARDANT, FLAME RETARDANT COMPOSITION, AND MOLDED PRODUCT AND MANUFACTURING METHOD THEREOF CBR3, CYP1B1, CYP1A1 GBA1 2344/4885EPHX2 1609/4885ALDH1A1 460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.