Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408920 | 0.78 | PDE4B (0.49) | PTGS2KDM4ECRHBPHTTCRHR2 | |
| SCHEMBL246300 | 0.78 | PTGS2 (0.46) | PTGS2NR1I2KDM4ECRHBPHTT | |
| SCHEMBL9214719 | 0.77 | PTGS2 (0.46) | PTGS2NR1I2PDE4BHDAC3HDAC1 | |
| SCHEMBL28376128 | 0.77 | PTGS2 (0.50) | PTGS2NR1I2KDM4ECRHBPHTT | |
| SCHEMBL25303952 | 0.75 | NR1I2 (0.54) | PTGS2NR1I2PDE4BHDAC3HDAC1 | |
| SCHEMBL303214 | 0.75 | NR1I2 (0.54) | PTGS2NR1I2PDE4BHDAC3HDAC1 | |
| SCHEMBL8523377 | 0.73 | THRB (0.49) | PDE4BHDAC3HDAC1HDAC2CA1 | |
| SCHEMBL10591928 | 0.73 | NR1I2 (0.47) | PTGS2NR1I2PDE4BHDAC3HDAC1 | |
| SCHEMBL7119167 | 0.72 | HPGD (0.47) | PTGS2NR1I2KDM4EPDE4BHDAC3 | |
| SCHEMBL135620 | 0.71 | HDAC3 (0.59) | PDE4BHDAC3HDAC1HDAC2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629400-B2 | Image making medium | HYMAN SYDNEY | 2009-12-08 | — | — | US | disclosed |
| US-20030035917-A1 | Image making medium | HYMAN SYDNEY (US) | 2003-02-20 | — | — | US | disclosed |
| US-4798822-A | PHOTOSTABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1989-01-17 | — | — | US | disclosed |
| US-4661594-A | PHOTODEGRADATION INHIBITION | CIBA-GEIGY CORPORATION (US) | 1987-04-28 | — | — | US | disclosed |