SCHEMBL4388846

SCHEMBL4388846

CC(C)OC(=O)CC1CC2C=CC1O2

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.36
TSHR P16473 1/20 0.32
LMNA P02545 2/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4378650 0.82 MIF (0.32) MIF
SCHEMBL1088535 0.75 SLC6A12 (0.42)
SCHEMBL11907987 0.74 MAPT (0.31)
SCHEMBL4384510 0.73 POLB (0.33) SMN1; SMN2
SCHEMBL4384163 0.72
SCHEMBL6367869 0.70 NLRP3 (0.39) TSHR
SCHEMBL4377524 0.69 KDM4E (0.41) MIFTSHRLMNASMN1; SMN2
SCHEMBL11688739 0.67 LMNA (0.41) MIFTSHRLMNASMN1; SMN2
SCHEMBL22263855 0.67 MIF (0.36) MIFTSHRLMNASMN1; SMN2
SCHEMBL11909022 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211984-B2 Ring-opening metathesis polymer, hydrogenated product thereof, method for preparing the same, and use thereof MITSUI CHEMICALS, INC. (JP) 2012-07-03 US disclosed
US-20090215974-A1 RING-OPENING METATHESIS POLYMER, HYDROGENATED PRODUCT THEREOF, METHOD FOR PREPARING THE SAME, AND USE THEREOF MITSUI CHEMICALS INC (JP) 2009-08-27 US disclosed
EP-2045280-A1 RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF Mitsui Chemicals, Inc. (JP) 2009-04-08 EP disclosed