Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | FABP7 | O15540 | 5/20 | 0.31 |
| ▸ | FABP3 | P05413 | 5/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4383543 | 0.74 | TSHR (0.34) | THRB | |
| SCHEMBL3746869 | 0.70 | THRB (0.47) | THRBMEN1RAB9AKMT2A | |
| SCHEMBL4388134 | 0.69 | TSHR (0.41) | THRB | |
| SCHEMBL8028277 | 0.68 | THRB (0.44) | THRBMEN1KMT2A | |
| SCHEMBL8044874 | 0.67 | TSHR (0.46) | THRBMEN1KMT2A | |
| SCHEMBL24595938 | 0.67 | KMT2A (0.63) | THRBFABP7FABP3FABP5MEN1 | |
| SCHEMBL23963473 | 0.66 | ALDH1A1 (0.46) | THRBMEN1RAB9AKMT2A | |
| SCHEMBL29384579 | 0.65 | THRB (0.53) | THRBMEN1KMT2A | |
| SCHEMBL68668 | 0.65 | THRB (0.53) | THRBMEN1KMT2A | |
| SCHEMBL7857605 | 0.64 | TSHR (0.41) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629424-B2 | Metal-containing compositions and method of making same | PRYOG, LLC (US) | 2009-12-08 | — | — | US | claimed |
| US-20080015278-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG, LLC | 2008-01-17 | — | — | US | claimed |
| WO-2007070092-A2 | METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME | PRYOG, LLC (US) | 2007-06-21 | — | — | WO | claimed |
| US-7629424-B2 | Metal-containing compositions and method of making same | PRYOG, LLC (US) | 2009-12-08 | — | — | US | disclosed |
| US-20080015278-A1 | Metal-Containing Compositions and Method of Making Same | PRYOG, LLC | 2008-01-17 | — | — | US | disclosed |
| WO-2007070092-A2 | METAL-CONTAINING COMPOSITIONS AND METHOD OF MAKING SAME | PRYOG, LLC (US) | 2007-06-21 | — | — | WO | disclosed |