SCHEMBL4389993

SCHEMBL4389993

CCC(C)(C)c1ccc([I+](OS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)c2ccc(C(C)(C)CC)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
MAPT P10636 1/20 0.38
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP3 P42574 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
POLB P06746 1/20 0.31
CYP2C9 P11712 1/20 0.31
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL503801 0.85 HDAC11 (0.37) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL5412257 0.82 HSD11B1 (0.38) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL5416235 0.81 NPC1 (0.38) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL1803566 0.81 CA1 (0.38) CA1CA2CYP2C9HDAC6
SCHEMBL5409951 0.80 CA2 (0.40) MAPTLMNASMN1; SMN2CA1CA2
SCHEMBL5412565 0.80 NPC1 (0.37) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL5398691 0.79 NPC1 (0.35) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL5410042 0.78 NPC1 (0.35) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL3753449 0.78 NPC1 (0.38) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL4868311 0.78 NPC1 (0.38) NPC1RAB9AMAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2477073-A1 Resist composition for electron beam, EUV or X-ray Fujifilm Corporation (JP) 2012-07-18 EP disclosed
US-7521168-B2 Compound that has a reduction potential higher than that of diphenyl iodonium salt and generates an acid upon irradiation of an actinic ray or radiation. FUJIFILM CORPORATION (JP) 2009-04-21 US disclosed
US-7312014-B2 Poly(p-hydroxystyrene/styrene/alkyl acrylate) terpolymer derivative and acid generator comprising triphenylsulfonium benzenesulfonate derivative; forming positive pattern using transcription technology in high vacuum with irradiated energy such as electron beam, extreme ultraviolet ray and X-ray WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2007-12-25 US disclosed
US-7214465-B2 Positive photosensitive composition FUJIFILM CORPORATION (JP) 2007-05-08 US disclosed
US-6887647-B2 Negative-working resist composition for electron beams or x-rays FUJI PHOTO FILM CO., LTD. (JP) 2005-05-03 US disclosed
US-20040170918-A1 Poly(p-hydroxystyrene/styrene/alkyl acrylate) terpolymer derivative and acid generator comprising triphenylsulfonium benzenesulfonate derivative; forming positive pattern using transcription technology in high vacuum with irradiated energy such as electron beam, extreme ultraviolet ray and X-ray WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2004-09-02 US disclosed
EP-1406123-A1 RESIST COMPOSITIONS Wako Pure Chemical Industries, Ltd. (JP) 2004-04-07 EP disclosed
US-20030224285-A1 Positive photosensitive composition FUJI PHOTO FILM CO., LTD. 2003-12-04 US disclosed
US-20030198894-A1 Resist composition for electron beam, EUV or X-ray FUJI PHOTO FILM CO., LTD. 2003-10-23 US disclosed
EP-1338921-A2 Resist composition for electron beam, X-ray or EUV Fuji Photo Film Co., Ltd. (JP) 2003-08-27 EP disclosed
US-20030054287-A1 Resist composition FUJI PHOTO FILM CO., LTD. 2003-03-20 US disclosed
US-20020192592-A1 Negative-working resist composition for electron beams or X-rays FUJI PHOTO FILM CO., LTD. 2002-12-19 US disclosed
US-20020058206-A1 Positive resist composition FUJI PHOTO FILM CO., LTD. 2002-05-16 US disclosed
EP-1193556-A1 Positive resist composition Fuji Photo Film Co., Ltd. (JP) 2002-04-03 EP disclosed