Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.62 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.62 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | GOT1 | P17174 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593633 | 0.86 | MAPT (0.77) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL4391929 | 0.86 | MAPT (0.71) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2405762 | 0.84 | MAPT (0.57) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL654537 | 0.78 | POLB (0.69) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL2093132 | 0.78 | MAPT (0.60) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30250340 | 0.77 | MEN1 (0.56) | MEN1KMT2AMAPTKDM4ENPC1 | |
| SCHEMBL20886934 | 0.77 | POLB (0.55) | TAS1R3TAS1R1TAS1R2MAPTKDM4E | |
| SCHEMBL4396084 | 0.77 | ALDH1A1 (0.76) | MEN1KMT2AMAPTKDM4EGOT1 | |
| SCHEMBL32660753 | 0.77 | ALDH1A1 (0.76) | MEN1KMT2AMAPTKDM4EGOT1 | |
| SCHEMBL702622 | 0.77 | TAS1R3 (1.00) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |