Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 3/20 | 0.55 |
| ▸ | PRKCG | P05129 | 3/20 | 0.55 |
| ▸ | PRKCB | P05771 | 3/20 | 0.55 |
| ▸ | PRKCA | P17252 | 3/20 | 0.55 |
| ▸ | PRKCH | P24723 | 3/20 | 0.55 |
| ▸ | PRKCI | P41743 | 3/20 | 0.55 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.55 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.55 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PRKACA | P17612 | 2/20 | 0.55 |
| ▸ | PRKACG | P22612 | 2/20 | 0.55 |
| ▸ | PRKACB | P22694 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394897 | 1.00 | PRKD3 (0.55) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL4390192 | 0.86 | NPY5R (0.67) | NPY5RNPY1RHPGDALDH1A1ADRA2A | |
| SCHEMBL4007555 | 0.86 | NPY5R (0.67) | NPY5RNPY1RHPGDALDH1A1ADRA2A | |
| SCHEMBL13590697 | 0.86 | ACACB (0.60) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL9192611 | 0.83 | PRKD3 (0.58) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL10554863 | 0.81 | PRKD3 (0.58) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL10553051 | 0.81 | NSD2 (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL4163565 | 0.80 | HPGD (0.68) | KMT2ALMNASMN1; SMN2NPY5RHPGD | |
| SCHEMBL4163570 | 0.80 | HPGD (0.68) | KMT2ALMNASMN1; SMN2NPY5RHPGD | |
| SCHEMBL30871841 | 0.77 | P2RX7 (0.52) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | claimed |
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306133-A1 | New Acetyl Coenzyme A Carboxylase (ACC) Inhibitors And Uses In Treatments Of Obesity And Diabetes Mellitus - 087 | ACACA, ACACB, ACAT1 | PRKD3 1824/4885PRKCG 798/4885PRKCB 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.