Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4399483 | 0.90 | HTR6 (0.61) | HTR6MAPTLMNAMEN1KMT2A | |
| SCHEMBL4393846 | 0.89 | HTR6 (0.57) | HTR6SMN1; SMN2TP53MAPT | |
| SCHEMBL3156792 | 0.85 | HTR6 (0.64) | HTR6LMNAMEN1KMT2A | |
| SCHEMBL4399061 | 0.85 | HTR6 (0.56) | HTR6LMNA | |
| SCHEMBL3147607 | 0.85 | HTR6 (0.62) | HTR6SMN1; SMN2LMNA | |
| SCHEMBL3152766 | 0.82 | HTR6 (0.56) | HTR6SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL3153572 | 0.82 | HTR6 (0.62) | HTR6SMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL4398501 | 0.82 | HTR6 (0.46) | HTR6MAPTLMNAMEN1KMT2A | |
| SCHEMBL4394298 | 0.81 | HTR6 (0.44) | HTR6SMN1; SMN2TP53MAPTLMNA | |
| SCHEMBL4392195 | 0.80 | HTR6 (0.44) | HTR6MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |