Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4398501 | 0.92 | HTR6 (0.46) | HTR6LMNAMAPTALDH1A1HTT | |
| SCHEMBL4397615 | 0.90 | HTR6 (0.49) | HTR6LMNAMAPTUSP2ALDH1A1 | |
| SCHEMBL4399061 | 0.89 | HTR6 (0.56) | HTR6LMNAOXTR | |
| SCHEMBL4402141 | 0.86 | HTR6 (0.56) | HTR6LMNAMAPTPKMMAPK10 | |
| SCHEMBL3146725 | 0.83 | HTR6 (0.61) | HTR6ALDH1A1OXTR | |
| SCHEMBL4399483 | 0.82 | HTR6 (0.61) | HTR6LMNAMAPTALDH1A1HTT | |
| SCHEMBL3147668 | 0.82 | HTR6 (0.56) | HTR6LMNAMAPTPKMKDM4E | |
| SCHEMBL4392195 | 0.82 | HTR6 (0.44) | HTR6LMNAMAPTUSP2ALDH1A1 | |
| SCHEMBL4394478 | 0.81 | HTR6 (0.56) | HTR6LMNAMAPTALDH1A1HTT | |
| SCHEMBL4390344 | 0.81 | HTR6 (0.55) | HTR6LMNAMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |