Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4394397 | 0.89 | HTR6 (0.72) | HTR6CHRM5CHRM4KDM2B | |
| SCHEMBL4390344 | 0.89 | HTR6 (0.55) | HTR6TP53SMN1; SMN2MAPT | |
| SCHEMBL3147607 | 0.88 | HTR6 (0.62) | HTR6SMN1; SMN2 | |
| SCHEMBL3152766 | 0.85 | HTR6 (0.56) | HTR6SMN1; SMN2 | |
| SCHEMBL3148711 | 0.85 | HTR6 (0.79) | HTR6SMN1; SMN2MAPT | |
| SCHEMBL4395155 | 0.84 | HTR6 (0.69) | HTR6CHRM5CHRM4KDM2B | |
| SCHEMBL3153572 | 0.81 | HTR6 (0.62) | HTR6SMN1; SMN2MAPT | |
| SCHEMBL3137601 | 0.81 | HTR6 (0.57) | HTR6CHRM5 | |
| SCHEMBL4402141 | 0.81 | HTR6 (0.56) | HTR6CHRM5TP53SMN1; SMN2CHRM4 | |
| SCHEMBL4394478 | 0.81 | HTR6 (0.56) | HTR6CHRM5CHRM4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |