Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385332 | 1.00 | ADRB2 (0.56) | ADRB2NPC1CHRM3 | |
| SCHEMBL4390551 | 1.00 | ADRB2 (0.56) | ADRB2NPC1CHRM3 | |
| SCHEMBL4385335 | 1.00 | ADRB2 (0.56) | ADRB2NPC1CHRM3 | |
| SCHEMBL4385654 | 0.99 | ADRB2 (0.55) | ADRB2NPC1CHRM3 | |
| SCHEMBL4385655 | 0.99 | ADRB2 (0.55) | ADRB2NPC1CHRM3 | |
| SCHEMBL4392221 | 0.98 | ADRB2 (0.54) | ADRB2NPC1CHRM3 | |
| SCHEMBL4392224 | 0.98 | ADRB2 (0.54) | ADRB2NPC1CHRM3 | |
| SCHEMBL4384879 | 0.96 | ADRB2 (0.56) | ADRB2NPC1 | |
| SCHEMBL4384875 | 0.96 | ADRB2 (0.56) | ADRB2NPC1 | |
| SCHEMBL4388455 | 0.94 | ADRB2 (0.53) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629358-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| US-7629358-B2 | Compounds useful for the treatment of diseases | PFIZER INC (US) | 2009-12-08 | — | — | US | disclosed |
| US-20050234097-A1 | Compounds useful for the treatment of diseases | PFIZER INC | 2005-10-20 | — | — | US | disclosed |
| EP-1577291-A1 | Phenylethanolamine derivatives as beta-2 agonists | Pfizer Limited (GB) | 2005-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234097-A1 | Compounds useful for the treatment of diseases | LTC4S, CYP11B2, CYP11B1 | ADRB2 731/4885NPC1 234/4885CHRM3 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.