SCHEMBL4390554

SCHEMBL4390554

CNC(C)Cc1cc(OC)cc(OC)c1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.48
SLC18A2 Q05940 1/20 0.48
SIGMAR1 Q99720 1/20 0.48
ALDH1A1 P00352 1/20 0.44
SLC6A4 P31645 2/20 0.43
CYP2D6 P10635 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4380664 0.83 TAAR1 (0.49) TAAR1SLC18A2SIGMAR1SLC6A4
SCHEMBL14655805 0.82 TAAR1 (0.67) TAAR1SLC18A2SIGMAR1
SCHEMBL178622 0.80 SLC6A4 (0.60) TAAR1SLC18A2SIGMAR1SLC6A4CYP2D6
SCHEMBL896368 0.80 SLC6A4 (0.60) TAAR1SLC18A2SIGMAR1SLC6A4CYP2D6
Methamphetamine SCHEMBL4380667 0.79 TAAR1 (0.68) TAAR1SLC18A2SIGMAR1
SCHEMBL171441 0.79 ALDH1A1 (0.52) TAAR1ALDH1A1SLC6A4
Hydrochloric Acid SCHEMBL29410112 0.78 SLC6A4 (0.58) TAAR1SLC18A2SIGMAR1SLC6A4CYP2D6
SCHEMBL16930148 0.78 KMT2A (0.54) TAAR1ALDH1A1SLC6A4CYP2D6SLC6A3
SCHEMBL16980897 0.78 ALDH1A1 (0.38) TAAR1ALDH1A1
SCHEMBL5297210 0.77 CYP2D6 (0.42) CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1062511-B1 IMMUNOASSAYS INVOLVING SURFACE ENHANCED RAMAN SCATTERING UNIV STRATHCLYDE (GB) 2009-11-25 EP disclosed
US-6750065-B1 FOR USE IN DRUG OR EXPLOSIVE DETECTION UNIVERSITY OF STRATHCLYDE (GB) 2004-06-15 US disclosed
EP-1062511-A1 IMMUNOASSAYS INVOLVING SURFACE ENHANCED RAMAN SCATTERING The University of Strathclyde (GB) 2000-12-27 EP disclosed
WO-1999044065-A1 IMMUNOASSAYS INVOLVING SURFACE ENHANCED RAMAN SCATTERING UNIVERSITY OF STRATHCLYDE (GB) 1999-09-02 WO disclosed