Pyrogallol

Pyrogallol

SCHEMBL4390779

CC1(C)CC2(CC(C)(C)c3cc(O)c(O)cc32)c2cc(O)c(O)cc21.Oc1cccc(O)c1O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
LMNA P02545 2/20 0.43
HPGD P15428 2/20 0.43
ALOX15 P16050 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ADAMTS4 O75173 1/20 0.43
EGFR P00533 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
FYN P06241 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
CA6 P23280 1/20 0.43
CDK2 P24941 1/20 0.43
MMP12 P39900 1/20 0.43
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ADAMTS5 Q9UNA0 1/20 0.43
TRPA1 O75762 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29569404 0.87 RXRA (0.35) ALDH1A1HPGDHSD17B10RECQLTDP1
SCHEMBL196263 0.87 RXRA (0.35) ALDH1A1HPGDHSD17B10RECQLTDP1
SCHEMBL16021623 0.84 RXRA (0.33) ACHERXRARARBMEN1KMT2A
SCHEMBL18656390 0.84 RXRA (0.33) ACHERXRARARBMEN1KMT2A
SCHEMBL9328056 0.79 OPRM1 (0.35) ALDH1A1LMNACYP3A4RXRARARB
SCHEMBL8895378 0.79
SCHEMBL14413579 0.78 KDM4E (0.35) ALDH1A1HPGDALOX15HSD17B10RECQL
SCHEMBL12387988 0.78 KDM4E (0.35) ALDH1A1HPGDALOX15HSD17B10RECQL
SCHEMBL12190600 0.78 KDM4E (0.35) ALDH1A1HPGDALOX15HSD17B10RECQL
SCHEMBL18088472 0.76 ALDH1A1 (0.35) ALDH1A1ALOX15HSD17B10RECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629400-B2 Image making medium HYMAN SYDNEY 2009-12-08 US disclosed
US-20030035917-A1 Image making medium HYMAN SYDNEY (US) 2003-02-20 US disclosed