Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.63 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AOC1 | P19801 | 3/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5616194 | 0.85 | DPP4 (0.59) | DPP4LOXL2PNMTADRB2 | |
| SCHEMBL30595830 | 0.83 | DPP4 (0.57) | DPP4LOXL2TDP1BLMHRH1 | |
| SCHEMBL1275952 | 0.83 | DPP4 (0.57) | DPP4LOXL2TDP1BLMHRH1 | |
| SCHEMBL30332536 | 0.80 | CYP2A6 (0.56) | DPP4LOXL2KDM4E | |
| SCHEMBL3711456 | 0.80 | DPP4 (0.50) | DPP4LOXL2ADRB2 | |
| SCHEMBL6730614 | 0.80 | DPP4 (0.50) | DPP4LOXL2ADRB2MEN1KMT2A | |
| SCHEMBL9400328 | 0.80 | CYP2A6 (0.56) | DPP4LOXL2KDM4E | |
| SCHEMBL1274801 | 0.79 | LOXL2 (0.50) | DPP4LOXL2ADRB2 | |
| SCHEMBL30332439 | 0.79 | DPP4 (0.49) | DPP4 | |
| SCHEMBL18677234 | 0.79 | DPP4 (0.49) | DPP4LOXL2TDP1NSD2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381348-A1 | BIFUNCTIONAL MACROCYCLIC CHELATE, CONJUGATE, METAL COMPLEX AND USE THEREOF | JYAMS PET RESEARCH & DEVELOPMENT LIMITED (CN) | 2023-11-30 | — | — | US | disclosed |
| US-20230381348-A1 | BIFUNCTIONAL MACROCYCLIC CHELATE, CONJUGATE, METAL COMPLEX AND USE THEREOF | JYAMS PET RESEARCH & DEVELOPMENT LIMITED (CN) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381348-A1 | BIFUNCTIONAL MACROCYCLIC CHELATE, CONJUGATE, METAL COMPLEX AND USE THEREOF | C9, CNKSR1, NBAS | DPP4 3777/4885LOXL2 4604/4885PNMT 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.