Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 4/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25001185 | 0.81 | NAAA (0.46) | MEN1KMT2AHTTALDH1A1LTA4H | |
| SCHEMBL6507711 | 0.80 | KCNN4 (0.40) | LMNAKDM4EMEN1POLBKMT2A | |
| SCHEMBL30534379 | 0.78 | KCNN4 (0.43) | LMNAKDM4EMEN1POLBKMT2A | |
| SCHEMBL23548035 | 0.78 | KCNN4 (0.39) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1177684 | 0.77 | HIF1A (0.44) | MEN1KMT2ACYP3A4L3MBTL1KCNN4 | |
| SCHEMBL10352222 | 0.75 | CYP19A1 (0.44) | LMNAKDM4EMEN1POLBKMT2A | |
| SCHEMBL28779165 | 0.74 | CYP3A4 (0.43) | KMT2ACYP3A4KCNN4CYP2C19HIF1A | |
| SCHEMBL27726754 | 0.73 | HIF1A (0.44) | MEN1POLBKMT2ACYP3A4KCNN4 | |
| SCHEMBL4391005 | 0.73 | CYP1A2 (0.40) | KDM4EMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL2816305 | 0.72 | ALDH1A1 (0.56) | LMNAMEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073767-B1 | METHODS, KITS AND COMPOSITIONS FOR DETECTING AND QUANTITATING TARGET SEQUENCES | BOSTON PROBES INC (US) | 2009-11-25 | — | — | EP | disclosed |
| US-7135563-B2 | Compositions for detecting target sequences | BOSTON PROBES, INC. (US) | 2006-11-14 | — | — | US | disclosed |
| US-20020058278-A1 | Methods, kits and compositions for detecting and quantitating target sequences | BOSTON PROBES, INC. (US) | 2002-05-16 | — | — | US | disclosed |
| US-6287772-B1 | USING PROBE-BASED HYBRIDIZATION ASSAYS. | BOSTON PROBES, INC. | 2001-09-11 | — | — | US | disclosed |
| EP-1073767-A1 | METHODS, KITS AND COMPOSITIONS FOR DETECTING AND QUANTITATING TARGET SEQUENCES | Boston Probes, Inc. (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055916-A1 | METHODS, KITS AND COMPOSITIONS FOR DETECTING AND QUANTITATING TARGET SEQUENCES | BOSTON PROBES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |