Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507711 | 0.82 | KCNN4 (0.40) | CYP1A2CYP2D6KCNN4CYP2C19HIF1A | |
| SCHEMBL30534379 | 0.80 | KCNN4 (0.43) | CYP1A2CYP2D6KCNN4CYP2C19HIF1A | |
| SCHEMBL23548035 | 0.77 | KCNN4 (0.39) | CYP1A2CYP2D6KCNN4CYP2C19HIF1A | |
| SCHEMBL28378741 | 0.77 | CYP1A2 (0.44) | CYP1A2CYP2D6KCNN4CYP2C19HIF1A | |
| SCHEMBL29697688 | 0.76 | MEN1 (0.36) | CYP1A2CYP2D6KCNN4ALDH1A1MEN1 | |
| SCHEMBL30471462 | 0.75 | LARS1 (0.48) | CYP1A2CYP2D6KIF11 | |
| SCHEMBL3401876 | 0.74 | OPRM1 (0.48) | CYP1A2CYP2D6KCNN4CYP2C19HIF1A | |
| SCHEMBL2816306 | 0.73 | ALDH1A1 (0.54) | CYP1A2CYP2D6CYP2C19ALDH1A1TDP1 | |
| SCHEMBL28779165 | 0.73 | CYP3A4 (0.43) | CYP1A2CYP2D6KCNN4CYP2C19HIF1A | |
| SCHEMBL4391010 | 0.73 | LMNA (0.43) | KCNN4CYP2C19HIF1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073767-B1 | METHODS, KITS AND COMPOSITIONS FOR DETECTING AND QUANTITATING TARGET SEQUENCES | BOSTON PROBES INC (US) | 2009-11-25 | — | — | EP | disclosed |
| US-7135563-B2 | Compositions for detecting target sequences | BOSTON PROBES, INC. (US) | 2006-11-14 | — | — | US | disclosed |
| US-20020058278-A1 | Methods, kits and compositions for detecting and quantitating target sequences | BOSTON PROBES, INC. (US) | 2002-05-16 | — | — | US | disclosed |
| US-6287772-B1 | USING PROBE-BASED HYBRIDIZATION ASSAYS. | BOSTON PROBES, INC. | 2001-09-11 | — | — | US | disclosed |
| EP-1073767-A1 | METHODS, KITS AND COMPOSITIONS FOR DETECTING AND QUANTITATING TARGET SEQUENCES | Boston Probes, Inc. (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055916-A1 | METHODS, KITS AND COMPOSITIONS FOR DETECTING AND QUANTITATING TARGET SEQUENCES | BOSTON PROBES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |