SCHEMBL4391329

SCHEMBL4391329

COC(=O)c1cc(C(C)(C)c2ccc(OC(=O)Oc3ccccc3)cc2)ccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
LMNA P02545 3/20 0.44
TSHR P16473 1/20 0.44
KDM4E B2RXH2 8/20 0.44
MAPT P10636 5/20 0.44
HSD17B10 Q99714 5/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
ATM Q13315 2/20 0.44
POLB P06746 1/20 0.44
CYP2D6 P10635 1/20 0.44
HPGD P15428 4/20 0.42
ALOX15 P16050 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7056539 0.92 HSD17B10 (0.51) LMNAKDM4EMAPTHSD17B10MEN1
SCHEMBL4390475 0.91 HSD17B10 (0.48) LMNAKDM4EMAPTHSD17B10MEN1
SCHEMBL4541202 0.91 CA12 (0.49) CA12CA1CA2CA7CA9
SCHEMBL4383880 0.86 MAPT (0.50) LMNAKDM4EMAPTHSD17B10MEN1
SCHEMBL11387862 0.85 HSD17B10 (0.51) LMNAKDM4EMAPTHSD17B10MEN1
SCHEMBL13609957 0.85 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL4395930 0.85 HSD17B10 (0.51) LMNAKDM4EMAPTHSD17B10MEN1
SCHEMBL4544026 0.84 ALDH1A1 (0.43) CA12CA1CA2CA7CA9
SCHEMBL4395924 0.84 CA1 (0.53) CA12CA1CA2CA7CA9
SCHEMBL4384821 0.83 HSD17B10 (0.53) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
EP-1016648-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES ASAHI CHEMICAL IND (JP) 2003-05-14 EP disclosed
US-6262210-B1 TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-17 US disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 CA12 668/4885CA1 1665/4885CA2 449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.