Arginine

Arginine

SCHEMBL4391507

C[C@@H](O)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)OC(=O)CN.NCC(=O)O.N[C@@H](CC(=O)O)C(=O)O.O=C(O)[C@@H]1CCCN1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL4394264 0.98
Arginine SCHEMBL6166841 0.96
Arginine SCHEMBL4390114 0.95 PRCP (0.31)
Arginine SCHEMBL2493806 0.94 KEAP1 (0.30)
Arginine SCHEMBL27649411 0.90 PRCP (0.34)
Arginine SCHEMBL4396599 0.89 PRCP (0.35)
Arginine SCHEMBL2497437 0.89 OTC (0.32)
Arginine SCHEMBL4398586 0.87 PRCP (0.36)
Arginine SCHEMBL28465970 0.86 PRCP (0.33)
Arginine SCHEMBL6535144 0.85 PRCP (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384117-B2 Connective tissue stimulating peptides OCTANE ORTHOBIOLOGICS INC. (CA) 2022-07-12 US disclosed
US-20190077831-A1 CONNECTIVE TISSUE STIMULATING PEPTIDES MILLENIUM BIOLOGIX INC. (CA) 2019-03-14 US disclosed
US-10202419-B2 Connective tissue stimulating peptides OCTANE ORTHOBIOLOGICS INC. (CA) 2019-02-12 US disclosed
US-20160237117-A1 CONNECTIVE TISSUE STIMULATING PEPTIDES MILLENIUM BIOLOGIX INC. (CA) 2016-08-18 US disclosed
US-9133236-B2 Connective tissue stimulating peptides MILLENIUM BIOLOGIX INC. (CA) 2015-09-15 US disclosed
US-20120156276-A1 Connective tissue stimulating peptides MILLENIUM BIOLOGIX INC. (CA) 2012-06-21 US disclosed
US-7491691-B2 Connective tissue stimulating peptides OCTANE ORTHOBIOLOGICS INC. (CA) 2009-02-17 US disclosed
US-20050288229-A1 Connective Tissue Stimulating Peptides MILLENIUM BIOLOGIX INC. (CA) 2005-12-29 US disclosed
EP-1504033-A2 CONNECTIVE TISSUE STIMULATING PEPTIDES MILLENIUM BIOLOGIX INC. (CA) 2005-02-09 EP disclosed
WO-2003093314-A2 CONNECTIVE TISSUE STIMULATING PEPTIDES MILLENIUM BIOLOGIX INC. (CA) 2003-11-13 WO disclosed