Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY4R | P50391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL6164492 | 0.94 | OTC (0.35) | OTCDDAH1NOS3NOS1NOS2 | |
| Arginine SCHEMBL4391507 | 0.89 | — | — | |
| Arginine SCHEMBL4394264 | 0.87 | — | — | |
| Arginine SCHEMBL28623187 | 0.86 | OTC (0.39) | OTCDDAH1NOS3NOS1NOS2 | |
| Arginine SCHEMBL2762369 | 0.85 | OTC (0.42) | OTCDDAH1NOS3NOS1NOS2 | |
| Arginine SCHEMBL3633339 | 0.85 | OTC (0.42) | OTCDDAH1NOS3NOS1NOS2 | |
| Arginine SCHEMBL3633342 | 0.85 | OTC (0.42) | OTCDDAH1NOS3NOS1NOS2 | |
| Arginine SCHEMBL6166841 | 0.84 | — | — | |
| Arginine SCHEMBL4390114 | 0.83 | PRCP (0.31) | — | |
| Arginine SCHEMBL2493806 | 0.83 | KEAP1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11384117-B2 | Connective tissue stimulating peptides | OCTANE ORTHOBIOLOGICS INC. (CA) | 2022-07-12 | — | — | US | claimed |
| US-20190077831-A1 | CONNECTIVE TISSUE STIMULATING PEPTIDES | MILLENIUM BIOLOGIX INC. (CA) | 2019-03-14 | — | — | US | claimed |
| US-10202419-B2 | Connective tissue stimulating peptides | OCTANE ORTHOBIOLOGICS INC. (CA) | 2019-02-12 | — | — | US | claimed |
| US-20160237117-A1 | CONNECTIVE TISSUE STIMULATING PEPTIDES | MILLENIUM BIOLOGIX INC. (CA) | 2016-08-18 | — | — | US | claimed |
| US-20120156276-A1 | Connective tissue stimulating peptides | MILLENIUM BIOLOGIX INC. (CA) | 2012-06-21 | — | — | US | claimed |
| US-20050288229-A1 | Connective Tissue Stimulating Peptides | MILLENIUM BIOLOGIX INC. (CA) | 2005-12-29 | — | — | US | claimed |
| US-11384117-B2 | Connective tissue stimulating peptides | OCTANE ORTHOBIOLOGICS INC. (CA) | 2022-07-12 | — | — | US | disclosed |
| US-20190077831-A1 | CONNECTIVE TISSUE STIMULATING PEPTIDES | MILLENIUM BIOLOGIX INC. (CA) | 2019-03-14 | — | — | US | disclosed |
| US-10202419-B2 | Connective tissue stimulating peptides | OCTANE ORTHOBIOLOGICS INC. (CA) | 2019-02-12 | — | — | US | disclosed |
| US-20160237117-A1 | CONNECTIVE TISSUE STIMULATING PEPTIDES | MILLENIUM BIOLOGIX INC. (CA) | 2016-08-18 | — | — | US | disclosed |
| US-9133236-B2 | Connective tissue stimulating peptides | MILLENIUM BIOLOGIX INC. (CA) | 2015-09-15 | — | — | US | disclosed |
| US-20120156276-A1 | Connective tissue stimulating peptides | MILLENIUM BIOLOGIX INC. (CA) | 2012-06-21 | — | — | US | disclosed |
| US-8029817-B2 | Silicon substituted oxyapatite | WARSAW ORTHOPEDIC, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-7498043-B2 | Silicon substituted oxyapatite | WARSAW ORTHOPEDIC, INC. (US) | 2009-03-03 | — | — | US | disclosed |
| US-7491691-B2 | Connective tissue stimulating peptides | OCTANE ORTHOBIOLOGICS INC. (CA) | 2009-02-17 | — | — | US | disclosed |
| US-20090030089-A1 | Silicon Substituted Oxyapatite | WARSAW ORTHOPEDIC, INC. (US) | 2009-01-29 | — | — | US | disclosed |
| EP-1584338-B1 | Silicon substituted oxyapatite | WARSAW ORTHOPEDIC INC (US) | 2009-01-21 | — | — | EP | disclosed |
| US-20050288229-A1 | Connective Tissue Stimulating Peptides | MILLENIUM BIOLOGIX INC. (CA) | 2005-12-29 | — | — | US | disclosed |
| US-20050244449-A1 | Silicon substituted oxyapatite | WARSAW ORTHOPEDIC, INC | 2005-11-03 | — | — | US | disclosed |
| EP-1584338-A2 | Silicon substituted oxyapatite | MILLENIUM BIOLOGIX INC. (CA) | 2005-10-12 | — | — | EP | disclosed |