Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415731 | 0.98 | ALOX15 (0.41) | ALOX15CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL7646255 | 0.82 | ALDH1A1 (0.37) | — | |
| SCHEMBL1899744 | 0.81 | ALOX15 (0.35) | ALOX15CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL7646259 | 0.81 | — | — | |
| SCHEMBL31582511 | 0.81 | CA2 (0.38) | ALOX15CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL677808 | 0.79 | ALOX15 (0.33) | ALOX15CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL20636934 | 0.76 | ALOX15 (0.31) | ALOX15CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL228835 | 0.73 | ALOX15 (0.34) | ALOX15CYP1A2SMN1; SMN2CYP2D6PKM | |
| SCHEMBL2130389 | 0.71 | ALOX15 (0.34) | ALOX15LMNAHSD17B10CHRNB2CHRNA4 | |
| SCHEMBL13630599 | 0.71 | TP53 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2730382-B1 | Method of treating wood | METSAELIITTO OSUUSKUNTA (FI) | 2018-11-21 | — | — | EP | claimed |
| EP-2730382-B1 | Method of treating wood | METSAELIITTO OSUUSKUNTA (FI) | 2018-11-21 | — | — | EP | disclosed |
| US-8771551-B2 | Method of treating wood | METSÄLIITTO OSUUSKUNTA (FI) | 2014-07-08 | — | — | US | disclosed |
| EP-2730382-A1 | Method of treating wood | Metsäliitto Osuuskunta (FI) | 2014-05-14 | — | — | EP | disclosed |
| US-20090304939-A1 | METHOD OF TREATING WOOD | METSALIITTO OSUUSKUNTA (FI) | 2009-12-10 | — | — | US | disclosed |