Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4392538 | 1.00 | GHSR (0.32) | GHSRSMN1; SMN2HDAC8KDM4EMEN1 | |
| SCHEMBL4392545 | 1.00 | GHSR (0.32) | GHSRSMN1; SMN2HDAC8KDM4EMEN1 | |
| SCHEMBL16399382 | 0.84 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL4610136 | 0.76 | — | — | |
| SCHEMBL4392635 | 0.76 | — | — | |
| SCHEMBL4392636 | 0.76 | — | — | |
| SCHEMBL25449261 | 0.74 | ALDH1A1 (0.40) | GHSRSMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL13545642 | 0.74 | ALDH1A1 (0.40) | GHSRSMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL16401433 | 0.73 | HSD17B10 (0.37) | ALDH1A1 | |
| SCHEMBL11902434 | 0.72 | GHSR (0.39) | GHSRSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |