Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13545642 | 1.00 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL4610136 | 0.97 | — | — | |
| SCHEMBL4405242 | 0.91 | MMP1 (0.38) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL14214481 | 0.89 | KDM4E (0.34) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL14952820 | 0.89 | GHSR (0.38) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL14320163 | 0.89 | SMN1; SMN2 (0.38) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL12869910 | 0.85 | HDAC8 (0.47) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL14457494 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL8998181 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL931066 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023079362-A1 | PROCESSABLE COMPOSITIONS AND USE FOR THE SAME | RIPPLE THERAPEUTICS CORPORATION (CA) | 2023-05-11 | — | — | WO | disclosed |