SCHEMBL665165

SCHEMBL665165

O=C1CCC(COCc2ccccc2)CCO1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
CTSL P07711 1/20 0.43
CTSB P07858 1/20 0.43
CTSK P43235 1/20 0.43
TAAR1 Q96RJ0 1/20 0.42
AKT1 P31749 1/20 0.39
TSHR P16473 1/20 0.39
BUB1 O43683 1/20 0.39
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
NFKB1 P19838 1/20 0.39
MAOB P27338 1/20 0.39
GRM5 P41594 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL421810 0.82 CTSL (0.49) LMNACTSLCTSBCTSKTSHR
SCHEMBL10000009 0.80 GLA (0.47) LMNANPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL4392777 0.78 TAAR1 (0.48) LMNACTSLCTSBCTSKTAAR1
SCHEMBL17019782 0.78 TSHR (0.58) LMNACTSLCTSBCTSKTAAR1
SCHEMBL1928095 0.78 TSHR (0.58) LMNACTSLCTSBCTSKTAAR1
SCHEMBL15060580 0.78 MEN1 (0.38) NPC1ALDH1A1HPGDNFKB1MAOB
SCHEMBL664313 0.77 SIGMAR1 (0.45) CTSLCTSBCTSKNPC1ALDH1A1
SCHEMBL4869082 0.76 CTSL (0.47) LMNACTSLCTSBCTSKAKT1
SCHEMBL4869078 0.76 CTSL (0.47) LMNACTSLCTSBCTSKAKT1
SCHEMBL19239030 0.75 SLC18A3 (0.43) TAAR1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
US-11180608-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-11-23 US disclosed
US-11180608-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-11-23 US disclosed
US-11149114-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-10-19 US disclosed
US-10980234-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2021-04-20 US disclosed
US-10779539-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC. (US) 2020-09-22 US disclosed
CN-107257813-B Block copolymers having surface active anchoring groups, compositions and methods thereof AZ电子材料卢森堡有限公司 2020-08-21 CN disclosed
EP-3259292-B1 BLOCK COPOLYMERS WITH SURFACE-ACTIVE JUNCTION GROUPS, COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MAT LUXEMBOURG SARL (LU) 2020-04-08 EP disclosed
US-10610597-B2 Polycarbonates bearing aromatic N-heterocycles for drug delivery INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-04-07 US disclosed
US-20110151566-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110151566-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110151566-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110152167-A1 BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
US-20100305300-A1 Method of Ring-Opening Polymerization, and Related Compositions and Articles INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
US-20100305300-A1 Method of Ring-Opening Polymerization, and Related Compositions and Articles INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11149114-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto DCLRE1A, ODC1, MRTO4 LMNA 1106/4885CTSL 3229/4885CTSB 2431/4885
US-11180608-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto DCLRE1A, ODC1, MRTO4 LMNA 1106/4885CTSL 3229/4885CTSB 2431/4885
US-10980234-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS LMNA 4337/4885CTSL 1974/4885CTSB 2418/4885
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS LMNA 4337/4885CTSL 1974/4885CTSB 2418/4885
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF MLEC, NOD2, PAM LMNA 1300/4885CTSL 3272/4885CTSB 2484/4885
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA LMNA 1875/4885CTSL 3374/4885CTSB 4040/4885
US-10779539-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS LMNA 4337/4885CTSL 1974/4885CTSB 2418/4885
US-20110152167-A1 BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO SAMM50, ADRM1, UFM1 LMNA 2738/4885CTSL 1944/4885CTSB 1698/4885
US-10610597-B2 Polycarbonates bearing aromatic N-heterocycles for drug delivery PAH, SULT1E1, SULT1A1 LMNA 3428/4885CTSL 4542/4885CTSB 1073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.