SCHEMBL4393348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10387783	0.86	ADRB1 (0.50)	ADRB1LMNAADRB2HTR1ASLC6A2
	Hydrochloric Acid SCHEMBL10479117	0.85	KDM4E (0.40)	ADRB1LMNAADRB2HTR1ASLC6A2
	SCHEMBL14414250	0.85	POLB (0.36)	KDM4EPOLBCYP2B6ALDH1A1GAA
	Hydrochloric Acid SCHEMBL10388921	0.84	LMNA (0.51)	ADRB1LMNAADRB2HTR1ASLC6A2
	Hydrochloric Acid SCHEMBL10388040	0.84	LMNA (0.51)	ADRB1LMNAADRB2HTR1ASLC6A2
	SCHEMBL27991480	0.83	ADRB1 (0.37)	ADRB1LMNAADRB2HTR1ASLC6A2
	SCHEMBL4396491	0.82	POLB (0.50)	TSHRPOLBHSD11B1HPGD
	Hydrochloric Acid SCHEMBL11643074	0.78	HDAC1 (0.35)	ADRB1LMNAADRB2HTR1ASLC6A2
	SCHEMBL11639419	0.76	DPP4 (0.32)	ADRB1LMNAADRB2HTR1ASLC6A2
	Hydrochloric Acid SCHEMBL11642403	0.76	ADRB2 (0.44)	ADRB1LMNAADRB2HTR1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.