SCHEMBL43934

SCHEMBL43934

CCOC(=O)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Acetate SCHEMBL3254085 0.91 ALDH1A1 (0.64)
SCHEMBL6007182 0.79
SCHEMBL5676975 0.79
SCHEMBL18446 0.77 ALDH1A1 (0.53)
SCHEMBL9126893 0.77 ALDH1A1 (0.36)
SCHEMBL288480 0.77 ALDH1A1 (0.53)
SCHEMBL5673494 0.75
SCHEMBL733363 0.74
SCHEMBL3029208 0.74
SCHEMBL2115865 0.74 ALDH1A1 (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1991 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283772-B Compound with cyclobutene structure and preparation method and application thereof 华南理工大学 2024-09-03 CN claimed
EP-3737676-B1 ACETAL COMPOUNDS AND THERAPEUTIC USES THEREOF LIGAND PHARM INC (US) 2024-03-06 EP claimed
CN-114890933-B Preparation method of racemic mitiglinide 恒升德康(南京)医药科技有限公司 2024-02-06 CN claimed
CN-115215798-B Aromatic cyanation synthesis method of inert olefin 恒升德康(南京)医药科技有限公司 2024-02-06 CN claimed
CN-116283772-A Compound with cyclobutene structure and preparation method and application thereof 华南理工大学 2023-06-23 CN claimed
CN-111517985-B Preparation method of 4- [ (1R) -1-amino-2-hydroxyethyl ] -3-fluoro-benzonitrile 济南百润医药科技有限公司 2023-05-12 CN claimed
CN-111943899-B Synthesis method of 5-ethyl formate tetrazole 河北凯诺中星科技有限公司 2023-04-21 CN claimed
CN-111675625-B Method for catalytic synthesis of tetrazoleacetic acid 九江中星医药化工有限公司 2022-11-04 CN claimed
CN-115215798-A Aromatic cyaniding synthesis method of inert olefin 恒升德康(南京)医药科技有限公司 2022-10-21 CN claimed
CN-112625004-B Novel photo-activated organic small molecule matrix, preparation method and application thereof in MALDI mass spectrometry detection 苏州大学 2022-10-11 CN claimed
WO-2002055843-A1 WELL TREATMENT FLUID COMPOSITIONS AND METHODS FOR THEIR USE BJ SERVICES COMPANY (US) 2002-07-18 WO claimed
EP-0889718-A1 KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRROLO-AZOLE COMPOUNDS, USE THEREOF AS COUPLERS, AND DYEING METHOD L'OREAL (FR) 1999-01-13 EP claimed
CN-1202828-A Substituted pyrzolyl benzenesulfonanides for use in veterinary SEARLE & CO (US) 1998-12-23 CN claimed
WO-1997035554-A1 KERATIN FIBRE DYE COMPOSITIONS CONTAINING PYRROLO-AZOLE COMPOUNDS, USE THEREOF AS COUPLERS, AND DYEING METHOD L'OREAL (FR) 1997-10-02 WO claimed
CN-1141630-A Substituted pyrazolyl benzenesulfonamides for treating inflammation SEARLE & CO (US) 1997-01-29 CN claimed
CN-1035664-A NEW CHEMICAL PROCESS MAY & BAKER LTD (GB) 1989-09-20 CN claimed
EP-0323885-A1 New chemical process MAY & BAKER LIMITED (GB) 1989-07-12 EP claimed
EP-0038541-B1 NOVEL PRODRUGS OF BIOLOGICALLY ACTIVE AGENTS CONTAINING MERCAPTO GROUPS, PROCESS FOR PREPARING AND THERAPEUTICALLY EFFECTIVE COMPOSITION CONTAINING THE SAME MERCK & CO. INC. (US) 1986-08-13 EP claimed
EP-0023938-B1 PREPARATION OF PYRROLE-2-ACETATES McNeilab, Inc. (US) 1983-07-20 EP claimed
US-4224279-A Reactive gas generator THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF COMMERCE (US) 1980-09-23 US claimed