SCHEMBL18446

SCHEMBL18446

CCOC(=O)C#CC(=O)OCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.53
LMNA P02545 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ALOX15 P16050 1/20 0.48
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
SOAT1 P35610 1/20 0.48
TRPA1 O75762 1/20 0.43
TSHR P16473 3/20 0.41
HCAR2 Q8TDS4 1/20 0.39
NPSR1 Q6W5P4 1/20 0.37
GLO1 Q04760 1/20 0.37
CYP1A2 P05177 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16811766 0.92 ALDH1A1 (0.50) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL6824967 0.89 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL1857628 0.89 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL2945943 0.89 GAA (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL2948744 0.88 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL16811720 0.87 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL2941847 0.87 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL16811738 0.87 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL7208877 0.87 ALOX15 (0.50) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL125810 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1622 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12358943-B1 Method of synthesizing testosterone-based thiazolidinone derivatives IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-07-15 US claimed
CN-119775321-A 4, 7-Diaryl thieno [2,3-d ] pyridazine iridium complex, and preparation method and application thereof 湖北文理学院 2025-04-08 CN claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
CN-115894559-B N, N' -bis (2-aminoethyl) -2, 3-bis (diphenylphosphoryl) succinamide and preparation method and application thereof 湖北大学 2024-08-23 CN claimed
CN-115260215-B Spiro polymer and preparation method and application thereof 北京理工大学 2024-02-13 CN claimed
CN-117263933-A Alpha-carboline derivative and synthesis method thereof 湘潭大学 2023-12-22 CN claimed
CN-117069947-A Phosphorus-containing polymer adhesive, lithium-sulfur battery, and preparation methods and applications thereof 武汉工程大学 2023-11-17 CN claimed
CN-116903652-A Preparation method of alkyl carborane 深圳技术大学 2023-10-20 CN claimed
CN-115894559-A N, N' -bis (2-aminoethyl) -2,3-bis (diphenylphosphoryl) succinamide and preparation method and application thereof 湖北大学 2023-04-04 CN claimed
CN-113461633-B 2-iminothiazolidinone alkenyl ester compounds and preparation method and application thereof 赣南师范大学 2023-03-28 CN claimed
US-20030073865-A1 PROCESS FOR PREPARING ETHANEBIS(ALKYLPHOSPHINIC) ACIDS CLARIANT GMBH 2003-04-17 US claimed
US-20020082447-A1 Process for preparing ethylenediphosphonic acids CLARIANT GMBH 2002-06-27 US claimed
EP-0957685-B1 INSECTICIDAL AND MITICIDAL COMPOSITIONS BASF AG (DE) 2002-03-06 EP claimed
US-5258062-A Ceramic packages for semiconductor devices SHINKO ELECTRIC INDUSTRIES CO., LTD. (JP) 1993-11-02 US claimed
US-5082871-A Acetylenedicarboxylate gelation inhibitor GENERAL ELECTRIC COMPANY (US) 1992-01-21 US claimed
US-4347346-A DIALKYLACETYLENEDICARBOXYITE TO PREVENT PREMATURE GELATION GENERAL ELECTRIC COMPANY (US) 1982-08-31 US claimed
US-4262107-A RELEASE COATINGS FOR PLASTICS AND PAPER GENERAL ELECTRIC COMPANY (US) 1981-04-14 US claimed
US-4048160-A Process for preparation of 7-alkoxy-3-bromomethylcephems ELI LILLY AND COMPANY (US) 1977-09-13 US claimed
US-4048163-A Process for preparation of 7-alkoxy-3-chloromethylcephems ELI LILLY AND COMPANY (US) 1977-09-13 US claimed
US-4042585-A Process for preparation of 3-halomethylcephems ELI LILLY AND COMPANY (US) 1977-08-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073865-A1 PROCESS FOR PREPARING ETHANEBIS(ALKYLPHOSPHINIC) ACIDS HAO2, ARSA, APEH ALDH1A1 912/4885LMNA 3674/4885HSD17B10 163/4885
US-12358943-B1 Method of synthesizing testosterone-based thiazolidinone derivatives ERG28, CYP17A1, AR ALDH1A1 1450/4885LMNA 3231/4885HSD17B10 319/4885
US-20020082447-A1 Process for preparing ethylenediphosphonic acids ENPP1, ALK, INPPL1 ALDH1A1 2080/4885LMNA 3509/4885HSD17B10 2470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.