Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18446 | 0.81 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL733363 | 0.79 | — | — | |
| SCHEMBL3029208 | 0.79 | — | — | |
| SCHEMBL2948744 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| Propynoic Acid Ethyl Ester SCHEMBL125800 | 0.77 | — | — | |
| SCHEMBL294547 | 0.77 | — | — | |
| SCHEMBL1387203 | 0.77 | — | — | |
| SCHEMBL43934 | 0.77 | — | — | |
| SCHEMBL16811766 | 0.75 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL125810 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427423-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | Optmed Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129068-A1 | IMPROVED METHYLIDENE MALONATE PROCESS | OPTMED INC. (US) | 2010-11-11 | — | — | WO | disclosed |
| US-7671230-B2 | Derivatization and solubilization of insoluble classes of fullerenes | TDA RESEARCH, INC. (US) | 2010-03-02 | — | — | US | disclosed |
| US-20090299078-A1 | SPECIFICALLY TAILORED ENDOHEDRAL METALLOFULLERENES | CLEMSON UNIVERSITY RESEARCH FOUNDATION | 2009-12-03 | — | — | US | disclosed |
| WO-2007103034-A2 | SPECIFICALLY TAILORED ENDOHEDRAL METALLOFULLERENES | CLEMSON UNIVERSITY (US) | 2007-09-13 | — | — | WO | disclosed |
| WO-2003029137-A2 | DERIVATIZATION AND SOLUBILIZATION OF INSOLUBLE CLASSES OF FULLERENES | TDA RESEARCH, INC. (US) | 2003-04-10 | — | — | WO | disclosed |
| US-20030065206-A1 | Derivatization and solubilization of insoluble classes of fullerenes | TDA RESEARCH, INC. | 2003-04-03 | — | — | US | disclosed |
| EP-0314280-B1 | Process for the preparation of fused pyridine compounds | UNIV PRINCETON (US) | 1996-02-21 | — | — | EP | disclosed |
| US-5473071-A | Process for the preparation of fused pyridine compounds | TRUSTEES OF PRINCETON UNIVERSITY (US) | 1995-12-05 | — | — | US | disclosed |
| US-4895946-A | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0314280-A2 | Process for the preparation of fused pyridine compounds | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-05-03 | — | — | EP | disclosed |
| EP-0157492-B1 | ELECTRON TRANSPORTING COMPOUNDS, ELECTROPHOTOGRAPHIC LAYERS AND ELEMENTS COMPRISING SUCH COMPOUNDS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-06-01 | — | — | EP | disclosed |
| EP-0157492-A2 | Electron transporting compounds, electrophotographic layers and elements comprising such compounds | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-10-09 | — | — | EP | disclosed |
| US-4514481-A | 4H-Thiopyran-1,1-dioxide and electrophotographic layers and elements comprising same | EASTMAN KODAK COMPANY (US) | 1985-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065206-A1 | Derivatization and solubilization of insoluble classes of fullerenes | MB, MYO1G, CD63 | ALDH1A1 1229/4885LMNA 1222/4885HSD17B10 1275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.