Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.56 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402081 | 0.90 | HTR6 (0.56) | HTR6CHRM5CHRM4 | |
| SCHEMBL4402141 | 0.90 | HTR6 (0.56) | HTR6CHRM5LMNACHRM4MEN1 | |
| SCHEMBL4401105 | 0.90 | HTR6 (0.56) | HTR6CHRM5EPHX2CHRM4 | |
| SCHEMBL4395155 | 0.89 | HTR6 (0.69) | HTR6CHRM5CHRM4 | |
| SCHEMBL4398501 | 0.89 | HTR6 (0.46) | HTR6EPHX2LMNAMEN1ALDH1A1 | |
| SCHEMBL3144543 | 0.87 | HTR6 (0.56) | HTR6LMNAMEN1ALDH1A1MAPT | |
| SCHEMBL4397244 | 0.87 | HTR6 (0.54) | HTR6CHRM5EPHX2CHRM4 | |
| SCHEMBL4394397 | 0.84 | HTR6 (0.72) | HTR6CHRM5EPHX2CHRM4 | |
| SCHEMBL3152545 | 0.84 | HTR6 (0.78) | HTR6EPHX2LMNAALDH1A1HTT | |
| SCHEMBL3142474 | 0.84 | HTR6 (0.52) | HTR6MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |