Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.72 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393846 | 0.89 | HTR6 (0.57) | HTR6CHRM5CHRM4KDM2B | |
| SCHEMBL4399483 | 0.89 | HTR6 (0.61) | HTR6CHRM5 | |
| SCHEMBL3152438 | 0.87 | HTR6 (0.73) | HTR6 | |
| SCHEMBL4395155 | 0.86 | HTR6 (0.69) | HTR6CHRM5CHRM4KDM2B | |
| SCHEMBL4394478 | 0.84 | HTR6 (0.56) | HTR6CHRM5EPHX2CHRM4 | |
| SCHEMBL3142878 | 0.84 | HTR6 (0.68) | HTR6 | |
| SCHEMBL3152764 | 0.84 | HTR6 (0.68) | HTR6 | |
| SCHEMBL4394394 | 0.84 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3147482 | 0.83 | HTR6 (0.66) | HTR6 | |
| SCHEMBL3152345 | 0.82 | HTR6 (0.68) | HTR6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |