Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11696808 | 0.81 | SMN1; SMN2 (0.47) | TRPA1ATMCYP3A4CYP1A2CYP2A6 | |
| SCHEMBL10106300 | 0.81 | SMN1; SMN2 (0.47) | TRPA1ATMCYP3A4CYP1A2CYP2A6 | |
| SCHEMBL29364976 | 0.81 | SMN1; SMN2 (0.47) | TRPA1ATMCYP3A4CYP1A2CYP2A6 | |
| SCHEMBL49551 | 0.81 | TRPA1 (0.46) | TRPA1ATMCYP3A4CYP1A2CYP2A6 | |
| SCHEMBL15854744 | 0.80 | ATM (0.41) | TRPA1ATMCYP3A4CYP1A2CYP2A6 | |
| SCHEMBL630878 | 0.78 | — | — | |
| SCHEMBL14669788 | 0.77 | TRPA1 (0.42) | TRPA1ATMCYP3A4CYP1A2CYP2A6 | |
| SCHEMBL30022899 | 0.77 | CYP3A4 (0.43) | TRPA1ATMCYP3A4CYP1A2CYP2A6 | |
| SCHEMBL1537728 | 0.77 | CYP3A4 (0.43) | TRPA1ATMCYP3A4CYP1A2CYP2A6 | |
| SCHEMBL3778547 | 0.77 | TRPA1 (0.42) | TRPA1ATMCYP3A4CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551956-B2 | Compositions containing peptides with non-natural amino acids and methods of use | AVON PRODUCTS, INC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-20090082252-A1 | Compositions Containing Peptides with Non-Natural Amino Acids and Methods of Use | AVON PRODUCTS INC. | 2009-03-26 | — | — | US | disclosed |
| EP-1998790-A2 | COMPOSITIONS CONTAINING PEPTIDES WITH NON-NATURAL AMINO ACIDS AND METHODS OF USE | AVON PRODUCTS, INC. (US) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007100874-A2 | COMPOSITIONS CONTAINING PEPTIDES WITH NON-NATURAL AMINO ACIDS AND METHODS OF USE | AVON PRODUCTS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| EP-1080079-A4 | THERMALLY STABLE TRIMETREXATES AND PROCESSES FOR PRODUCING THE SAME | US BIOSCIENCE (US) | 2001-10-04 | — | — | EP | disclosed |
| US-6258952-B1 | CRYSTALLIZATION | MEDIMMUNE ONCOLOGY, INC. | 2001-07-10 | — | — | US | disclosed |
| EP-1080079-A1 | THERMALLY STABLE TRIMETREXATES AND PROCESSES FOR PRODUCING THE SAME | U.S. BIOSCIENCE, INC. (US) | 2001-03-07 | — | — | EP | disclosed |
| US-6017922-A | Thermally stable trimetrexates and processes for producing the same | U.S. BIOSCIENCE, INC. (US) | 2000-01-25 | — | — | US | disclosed |
| WO-1999059981-A1 | THERMALLY STABLE TRIMETREXATES AND PROCESSES FOR PRODUCING THE SAME | U.S. BIOSCIENCE, INC. (US) | 1999-11-25 | — | — | WO | disclosed |
| US-5069708-A | PRE-AND POSTEMERGENCE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| US-4576753-A | MICROBIOCIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| US-4559345-A | Pyrimidine and s-triazine derivatives with antilipidemic activity | LBP ISTITUTO FARACEUTICO S.P.A. (IT) | 1985-12-17 | — | — | US | disclosed |
| US-4472309-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |
| EP-0073328-A1 | Novel pyrimidine and s. triazine derivatives with antilipidemic activity | LPB Istituto Farmaceutico s.p.a. (IT) | 1983-03-09 | — | — | EP | disclosed |
| US-4304718-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-08 | — | — | US | disclosed |
| US-4254214-A | BLACK, REDUCTION OF COPPER SALT OR COMPLEX TO COPPER | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-03 | — | — | US | disclosed |
| US-4181800-A | ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082252-A1 | Compositions Containing Peptides with Non-Natural Amino Acids and Methods of Use | CUTA, NGLY1, LNPEP | TRPA1 2189/4885ATM 4147/4885CYP3A4 4882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.