Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402141 | 0.90 | HTR6 (0.56) | HTR6CHRM5CHRM4KDM2BRXFP1 | |
| SCHEMBL4401105 | 0.89 | HTR6 (0.56) | HTR6CHRM5CHRM4KDM2BCHRM1 | |
| SCHEMBL4395155 | 0.88 | HTR6 (0.69) | HTR6CHRM5CHRM4KDM2B | |
| SCHEMBL3147534 | 0.87 | HTR6 (0.54) | HTR6 | |
| SCHEMBL4402081 | 0.87 | HTR6 (0.56) | HTR6CHRM5CHRM4 | |
| SCHEMBL4394478 | 0.87 | HTR6 (0.56) | HTR6CHRM5CHRM4EPHX2 | |
| SCHEMBL3140246 | 0.84 | HTR6 (0.77) | HTR6 | |
| SCHEMBL4397820 | 0.82 | HTR6 (0.54) | HTR6CHRM5CHRM4KDM2BCHRM1 | |
| SCHEMBL4394397 | 0.82 | HTR6 (0.72) | HTR6CHRM5CHRM4KDM2BEPHX2 | |
| SCHEMBL3148997 | 0.81 | HTR6 (0.50) | HTR6RXFP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-B1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2009-12-09 | — | — | EP | claimed |