Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 8/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.46 |
| ▸ | EYA3 | Q99504 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | EYA2 | O00167 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849716 | 0.81 | TTR (0.60) | TTRSLC22A12CYP2C19EYA3CYP2C9 | |
| SCHEMBL5483047 | 0.70 | MEN1 (0.41) | TTRSLC22A12CYP2C19EYA3CYP2C9 | |
| SCHEMBL5063026 | 0.69 | SLC22A12 (0.39) | TTRSLC22A12CYP2C19EYA3CYP2C9 | |
| SCHEMBL28104532 | 0.69 | CYP2C19 (0.62) | TTRSLC22A12CYP2C19EYA3CYP2C9 | |
| SCHEMBL30258603 | 0.67 | TTR (0.76) | TTRSLC22A12CYP2C19EYA3CYP2C9 | |
| SCHEMBL6336631 | 0.67 | TTR (0.78) | TTRSLC22A12CYP2C19EYA3CYP2C9 | |
| SCHEMBL30258692 | 0.66 | TTR (0.68) | TTRSLC22A12CYP2C19EYA3CYP2C9 | |
| SCHEMBL719026 | 0.65 | EYA3 (0.48) | TTRSLC22A12CYP2C19EYA3CYP2C9 | |
| SCHEMBL28078332 | 0.65 | SLC22A12 (0.58) | TTRSLC22A12EYA3CYP2C9KMT2A | |
| Benzbromarone SCHEMBL19205474 | 0.63 | SLC22A12 (1.00) | TTRSLC22A12CYP2C19EYA3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498301-B2 | Composition containing dipeptide of histidine and alanine for reducing uric acid and method for reducing uric acid using the dipeptide | LYTONE ENTERPRISE, INC. (TW) | 2009-03-03 | — | — | US | claimed |