Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.40 |
| ▸ | EYA3 | Q99504 | 5/20 | 0.40 |
| ▸ | TTR | P02766 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28104534 | 0.71 | SLC22A12 (0.40) | MEN1KMT2ASLC22A12EYA3TTR | |
| SCHEMBL4394481 | 0.70 | TTR (0.46) | MEN1KMT2APLA2G1BATG4BSLC22A12 | |
| SCHEMBL28078332 | 0.69 | SLC22A12 (0.58) | KMT2ASLC22A12EYA3TTRPPARG | |
| SCHEMBL28294570 | 0.69 | TTR (0.48) | MEN1KMT2ASLC22A12EYA3TTR | |
| SCHEMBL6058629 | 0.64 | ALDH5A1 (0.50) | KDM4EALDH1A1MAPTAPPABCB1 | |
| SCHEMBL7085914 | 0.61 | MEN1 (0.57) | MEN1KMT2APLA2G1BSLC22A12TTR | |
| SCHEMBL14185242 | 0.60 | PPARG (0.65) | MEN1KMT2ASLC22A12TTRPPARG | |
| SCHEMBL7499188 | 0.60 | PTPN1 (0.74) | MEN1KMT2ASLC22A12EYA3TTR | |
| SCHEMBL24812550 | 0.60 | USP7 (0.46) | ESR1ESR2 | |
| SCHEMBL30751581 | 0.60 | CYP3A4 (0.72) | MEN1KMT2APLA2G1BSLC22A12TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062198-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECHNOLOGY, INC. (US) | 2007-05-31 | — | — | WO | disclosed |