Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL4391881 | 0.95 | MEN1 (0.46) | SLC22A1KDM4EALDH1A1TDP1SLC6A4 | |
| SCHEMBL4398580 | 0.79 | SLC6A4 (0.57) | SLC22A1SLC6A4SLC6A2MEN1KMT2A | |
| SCHEMBL4394653 | 0.74 | SLC6A4 (0.56) | SLC22A1SLC6A4SLC6A2MEN1KMT2A | |
| SCHEMBL4391875 | 0.74 | SLC6A4 (0.56) | SLC22A1SLC6A4SLC6A2MEN1KMT2A | |
| SCHEMBL24136195 | 0.65 | L3MBTL1 (0.61) | KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL31302989 | 0.65 | L3MBTL1 (0.64) | KDM4ETDP1MEN1KMT2AOPRM1 | |
| SCHEMBL2777259 | 0.65 | L3MBTL1 (0.64) | KDM4ETDP1MEN1KMT2AOPRM1 | |
| SCHEMBL5067089 | 0.65 | LMNA (0.70) | KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL30885868 | 0.65 | LMNA (0.70) | KDM4EALDH1A1TDP1KMT2A | |
| SCHEMBL11646688 | 0.65 | TSHR (0.71) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1988398-B1 | Immunoassay for tramadol and its major metabolites | RANDOX LAB LTD (GB) | 2009-12-16 | — | — | EP | disclosed |
| EP-1988398-A1 | Immunoassay for tramadol and its major metabolites | Randox Laboratories Ltd. (GB) | 2008-11-05 | — | — | EP | disclosed |