SCHEMBL4395032

SCHEMBL4395032

NC(=O)CCC(=O)N=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16672200 0.86 KMT2A (0.32)
SCHEMBL21116024 0.86 KMT2A (0.37)
SCHEMBL14641650 0.84 LMNA (0.31)
SCHEMBL25666251 0.83 KMT2A (0.40)
Succinamide SCHEMBL28157588 0.77 LMNA (0.50)
Succinamide SCHEMBL36057 0.77
SCHEMBL9733473 0.74
SCHEMBL21782499 0.73 CASP2 (0.43)
Succinamide SCHEMBL11662331 0.73
Succinamide SCHEMBL21530847 0.73 LMNA (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010007893-A1 Carbonyl containing compounds EXXON RESEARCH & ENGINEERING CO. 2001-07-12 US claimed
US-6077915-A Carbonyl containing compounds EXXON RESEARCH & ENGINEERING (US) 2000-06-20 US claimed
EP-3257887-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-12-20 EP disclosed
EP-2326359-B1 POLYMERIC, DEGRADABLE DRUG-ELUTING STENTS AND COATINGS TEPHA INC (US) 2017-06-21 EP disclosed
WO-2015151048-A1 CAPPED AND UNCAPPED RNA MOLECULES AND BLOCK COPOLYMERS FOR INTRACELLULAR DELIVERY OF RNA INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2015-10-08 WO disclosed
US-20140045232-A1 ENZYME USED IN BIOSYNTHESIS OF 1, 4-BDO AND SCREENING METHOD OF THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-02-13 US disclosed
EP-2546255-A1 BENZAZEPINE COMPOUND Astellas Pharma Inc. (JP) 2013-01-16 EP disclosed
US-20110190866-A1 POLYMERIC, DEGRADABLE DRUG-ELUTING STENTS AND COATINGS TEPHA, INC. 2011-08-04 US disclosed
US-20090012008-A1 Pharmaceutical Composition for Photodynamic Therapy and a Method for Treating Oncological Diseases by Using Said Composition VALENTIN VIKTOROVICH PETROV (RU) 2009-01-08 US disclosed